Genome sequences of two highly colistin-resistant Pseudomonas aeruginosa clinical isolates from the cystic fibrosis lung

Anne E. Mattingly; Yohei Doi; Christian Melander

doi:10.1128/mra.00558-25

Genome sequences of two highly colistin-resistant Pseudomonas aeruginosa clinical isolates from the cystic fibrosis lung

Anne E. Mattingly
, Yohei Doi
, Christian Melander

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

1 被引用数 (Scopus)

抄録

The genomes of two highly colistin-resistant strains of Pseudomonas aeruginosa (MICs ≥ 1,024 mg/mL) isolated from cystic fibrosis lung infections were sequenced and analyzed. Genes associated with colistin resistance (pmrAB, phoPQ) showed unique mutations compared to other strains with similar resistance levels.

本文言語	英語
ジャーナル	Genome Announcements
巻	14
号	12
DOI	https://doi.org/10.1128/mra.00558-25
出版ステータス	出版済み - 12-2025
外部発表	はい

All Science Journal Classification (ASJC) codes

分子生物学
免疫学および微生物学（その他）
遺伝学

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10.1128/mra.00558-25

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title = "Genome sequences of two highly colistin-resistant Pseudomonas aeruginosa clinical isolates from the cystic fibrosis lung",

abstract = "The genomes of two highly colistin-resistant strains of Pseudomonas aeruginosa (MICs ≥ 1,024 mg/mL) isolated from cystic fibrosis lung infections were sequenced and analyzed. Genes associated with colistin resistance (pmrAB, phoPQ) showed unique mutations compared to other strains with similar resistance levels.",

keywords = "Pseudomonas aeruginosa, antibiotic resistance, colistin, cystic fibrosis",

author = "Mattingly, \{Anne E.\} and Yohei Doi and Christian Melander",

note = "Publisher Copyright: Copyright {\textcopyright} 2025 Mattingly et al.",

year = "2025",

month = dec,

doi = "10.1128/mra.00558-25",

language = "English",

volume = "14",

journal = "Genome Announcements",

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T1 - Genome sequences of two highly colistin-resistant Pseudomonas aeruginosa clinical isolates from the cystic fibrosis lung

AU - Mattingly, Anne E.

AU - Doi, Yohei

AU - Melander, Christian

PY - 2025/12

Y1 - 2025/12

N2 - The genomes of two highly colistin-resistant strains of Pseudomonas aeruginosa (MICs ≥ 1,024 mg/mL) isolated from cystic fibrosis lung infections were sequenced and analyzed. Genes associated with colistin resistance (pmrAB, phoPQ) showed unique mutations compared to other strains with similar resistance levels.

AB - The genomes of two highly colistin-resistant strains of Pseudomonas aeruginosa (MICs ≥ 1,024 mg/mL) isolated from cystic fibrosis lung infections were sequenced and analyzed. Genes associated with colistin resistance (pmrAB, phoPQ) showed unique mutations compared to other strains with similar resistance levels.

KW - Pseudomonas aeruginosa

KW - antibiotic resistance

KW - colistin

KW - cystic fibrosis

UR - https://www.scopus.com/pages/publications/105024800571

UR - https://www.scopus.com/pages/publications/105024800571#tab=citedBy

U2 - 10.1128/mra.00558-25

DO - 10.1128/mra.00558-25

M3 - Article

AN - SCOPUS:105024800571

SN - 2169-8287

VL - 14

JO - Genome Announcements

JF - Genome Announcements

IS - 12

ER -

Genome sequences of two highly colistin-resistant Pseudomonas aeruginosa clinical isolates from the cystic fibrosis lung

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All Science Journal Classification (ASJC) codes

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