Glycoproteins gM and gN of pseudorabies virus are dispensable for viral penetration and propagation in the nervous systems of adult mice

Marie Jo Masse, Alice Jöns, Johannes M. Dijkstra, Thomas C. Mettenleiter, Anne Flamand

研究成果: Article

11 引用 (Scopus)

抜粋

Glycoproteins gM and gN are conserved throughout the herpesviruses but are dispensable for viral replication in cell cultures. To assay for a function of these proteins in infection of an animal, deletion mutants of pseudorabies virus lacking gM or gN and corresponding revertants were analyzed for the ability to penetrate and propagate in the nervous systems of adult mice after intranasal inoculation. We demonstrate that neither of the two glycoproteins is required for infection of the nervous systems of mice by pseudorabies virus.

元の言語English
ページ(範囲)10503-10507
ページ数5
ジャーナルJournal of Virology
73
発行部数12
出版物ステータスPublished - 01-12-1999
外部発表Yes

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

フィンガープリント Glycoproteins gM and gN of pseudorabies virus are dispensable for viral penetration and propagation in the nervous systems of adult mice' の研究トピックを掘り下げます。これらはともに一意のフィンガープリントを構成します。

  • これを引用