Grade 3 lymphomatoid granulomatosis in a patient receiving methotrexate therapy for rheumatoid arthritis

Hiroshi Oiwa; Keichiro Mihara; Takanobu Kan; Maiko Tanaka; Hajime Shindo; Kazuhiko Kumagai; Eiji Sugiyama

doi:10.2169/internalmedicine.53.2593

Grade 3 lymphomatoid granulomatosis in a patient receiving methotrexate therapy for rheumatoid arthritis

Hiroshi Oiwa
, Keichiro Mihara
, Takanobu Kan
, Maiko Tanaka
, Hajime Shindo
, Kazuhiko Kumagai
, Eiji Sugiyama

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

15 被引用数 (Scopus)

抄録

Lymphomatoid granulomatosis (LyG) is a rare, B-cell derived, lymphoproliferative disorder that often presents as pulmonary nodular lesions with a histopathology of lymphatic invasion of the vascular wall. The development of LyG may be associated with reactivation of the Epstein-Barr virus under an immunosuppressive state. We herein report a case of Grade 3 LyG that developed during methotrexate therapy for rheumatoid arthritis and regressed following the withdrawal of the drug.

本文言語	英語
ページ（範囲）	1873-1875
ページ数	3
ジャーナル	Internal Medicine
巻	53
号	16
DOI	https://doi.org/10.2169/internalmedicine.53.2593
出版ステータス	出版済み - 2014
外部発表	はい

All Science Journal Classification (ASJC) codes

内科学

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10.2169/internalmedicine.53.2593

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title = "Grade 3 lymphomatoid granulomatosis in a patient receiving methotrexate therapy for rheumatoid arthritis",

abstract = "Lymphomatoid granulomatosis (LyG) is a rare, B-cell derived, lymphoproliferative disorder that often presents as pulmonary nodular lesions with a histopathology of lymphatic invasion of the vascular wall. The development of LyG may be associated with reactivation of the Epstein-Barr virus under an immunosuppressive state. We herein report a case of Grade 3 LyG that developed during methotrexate therapy for rheumatoid arthritis and regressed following the withdrawal of the drug.",

keywords = "Lymphomatoid granulomatosis, Methotrexate (MTX), Rheumatoid arthritis",

author = "Hiroshi Oiwa and Keichiro Mihara and Takanobu Kan and Maiko Tanaka and Hajime Shindo and Kazuhiko Kumagai and Eiji Sugiyama",

note = "Publisher Copyright: {\textcopyright} 2014 The Japanese Society of Internal Medicine.",

year = "2014",

doi = "10.2169/internalmedicine.53.2593",

language = "English",

volume = "53",

pages = "1873--1875",

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TY - JOUR

T1 - Grade 3 lymphomatoid granulomatosis in a patient receiving methotrexate therapy for rheumatoid arthritis

AU - Oiwa, Hiroshi

AU - Mihara, Keichiro

AU - Kan, Takanobu

AU - Tanaka, Maiko

AU - Shindo, Hajime

AU - Kumagai, Kazuhiko

AU - Sugiyama, Eiji

PY - 2014

Y1 - 2014

N2 - Lymphomatoid granulomatosis (LyG) is a rare, B-cell derived, lymphoproliferative disorder that often presents as pulmonary nodular lesions with a histopathology of lymphatic invasion of the vascular wall. The development of LyG may be associated with reactivation of the Epstein-Barr virus under an immunosuppressive state. We herein report a case of Grade 3 LyG that developed during methotrexate therapy for rheumatoid arthritis and regressed following the withdrawal of the drug.

AB - Lymphomatoid granulomatosis (LyG) is a rare, B-cell derived, lymphoproliferative disorder that often presents as pulmonary nodular lesions with a histopathology of lymphatic invasion of the vascular wall. The development of LyG may be associated with reactivation of the Epstein-Barr virus under an immunosuppressive state. We herein report a case of Grade 3 LyG that developed during methotrexate therapy for rheumatoid arthritis and regressed following the withdrawal of the drug.

KW - Lymphomatoid granulomatosis

KW - Methotrexate (MTX)

KW - Rheumatoid arthritis

UR - https://www.scopus.com/pages/publications/84906771303

UR - https://www.scopus.com/pages/publications/84906771303#tab=citedBy

U2 - 10.2169/internalmedicine.53.2593

DO - 10.2169/internalmedicine.53.2593

M3 - Article

C2 - 25130128

AN - SCOPUS:84906771303

SN - 0918-2918

VL - 53

SP - 1873

EP - 1875

JO - Internal Medicine

JF - Internal Medicine

IS - 16

ER -

Grade 3 lymphomatoid granulomatosis in a patient receiving methotrexate therapy for rheumatoid arthritis

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