抄録
We report a case of granulocyte colony-stimulating factor (G-CSF) producing lung cancer. A 38-year-old Japanese woman had a large cell undifferentiated carcinoma of the left lung with severe granulocytosis without any evidence of infection. A specimen was taken from a metastatic cervical lymph node and a tumor cell line was established. The culture supernatant of the line as well as patient's serum exhibited a high level of G-CSF by sandwich enzyme immunoassay. Immunohistochemical analysis demonstrated that tumor cells from transplanted nude mice were stained granularly in the cytoplasma by anti-human G-CSF monoclonal antibody, 4A6.
本文言語 | English |
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ページ(範囲) | 277-280 |
ページ数 | 4 |
ジャーナル | Internal medicine (Tokyo, Japan) |
巻 | 31 |
号 | 2 |
DOI | |
出版ステータス | Published - 02-1992 |
外部発表 | はい |
All Science Journal Classification (ASJC) codes
- 内科学