Granulocyte colony-stimulating factor-producing large cell undifferentiated carcinoma of the lung.

N. Shijubo, Y. Inoue, M. Hirasawa, T. Igarashi, M. Mori, A. Matsuura, T. Uede, A. Suzuki

研究成果: Article査読

39 被引用数 (Scopus)

抄録

We report a case of granulocyte colony-stimulating factor (G-CSF) producing lung cancer. A 38-year-old Japanese woman had a large cell undifferentiated carcinoma of the left lung with severe granulocytosis without any evidence of infection. A specimen was taken from a metastatic cervical lymph node and a tumor cell line was established. The culture supernatant of the line as well as patient's serum exhibited a high level of G-CSF by sandwich enzyme immunoassay. Immunohistochemical analysis demonstrated that tumor cells from transplanted nude mice were stained granularly in the cytoplasma by anti-human G-CSF monoclonal antibody, 4A6.

本文言語English
ページ(範囲)277-280
ページ数4
ジャーナルInternal medicine (Tokyo, Japan)
31
2
DOI
出版ステータスPublished - 02-1992
外部発表はい

All Science Journal Classification (ASJC) codes

  • 内科学

フィンガープリント

「Granulocyte colony-stimulating factor-producing large cell undifferentiated carcinoma of the lung.」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル