TY - JOUR
T1 - Green tea consumption and cerebral white matter lesions in community-dwelling older adults without dementia
AU - On behalf of the Japan Prospective Studies Collaboration for Aging and Dementia (JPSC-AD) study group
AU - Shibata, Shutaro
AU - Noguchi-Shinohara, Moeko
AU - Shima, Ayano
AU - Ozaki, Taro
AU - Usui, Yuta
AU - Taki, Yasuyuki
AU - Uchida, Kazuhiro
AU - Honda, Takanori
AU - Hata, Jun
AU - Ohara, Tomoyuki
AU - Mikami, Tatsuya
AU - Maeda, Tetsuya
AU - Mimura, Masaru
AU - Nakashima, Kenji
AU - Iga, Jun Ichi
AU - Takebayashi, Minoru
AU - Ninomiya, Toshiharu
AU - Ono, Kenjiro
AU - Kiyohara, Yutaka
AU - Kubo, Michiaki
AU - Terao, Chikashi
AU - Momozawa, Yukihide
AU - Ri, Izen
AU - Inoue, Yusuke
AU - Muto, Kaori
AU - Yoshida, Hisako
AU - Thyreau, Benjamin
AU - Tatewaki, Yasuko
AU - Esaki, Midori
AU - Kokubo, Yoshihiro
AU - Ikeda, Manabu
AU - Hashimoto, Mamoru
AU - Koyama, Asuka
AU - Fukuhara, Ryuji
AU - Yuki, Seiji
AU - Ishikawa, Tomohisa
AU - Miyagawa, Yusuke
AU - Kajitani, Naoto
AU - Ueno, Shu Ichi
AU - Yoshino, Yuta
AU - Tachibana, Ayumi
AU - Ozaki, Tomoki
AU - Kishi, Masafumi
AU - Wada, Kenji
AU - Nakano, Toshiya
AU - Kowa, Hisanori
AU - Fukada, Yasuyo
AU - Kida, Hisashi
AU - Shikimoto, Ryo
AU - Niimura, Hidehito
N1 - Publisher Copyright:
© The Author(s) 2025.
PY - 2025/12
Y1 - 2025/12
N2 - This study investigated the association between green tea or coffee consumption with cerebral white matter lesions and hippocampal and total brain volumes among 8766 community-dwelling participants recruited from the Japan Prospective Studies Collaboration for Aging and Dementia between 2016 and 2018. A Food Frequency Questionnaire was used to assess green tea and coffee consumption, whereas brain magnetic resonance imaging was performed to assess cerebral white matter lesions, hippocampal volume, and total brain volume. Multivariable-adjusted analysis revealed significant correlations between fewer cerebral white matter lesions and higher green tea consumption, whereas no significant differences were found between green tea consumption and hippocampal or total brain volume. Regarding coffee consumption, no significant differences were observed in cerebral white matter lesions or hippocampal or total brain volumes. Hence, higher green tea consumption was associated with fewer cerebral white matter lesions, suggesting that it may be useful in preventing dementia.
AB - This study investigated the association between green tea or coffee consumption with cerebral white matter lesions and hippocampal and total brain volumes among 8766 community-dwelling participants recruited from the Japan Prospective Studies Collaboration for Aging and Dementia between 2016 and 2018. A Food Frequency Questionnaire was used to assess green tea and coffee consumption, whereas brain magnetic resonance imaging was performed to assess cerebral white matter lesions, hippocampal volume, and total brain volume. Multivariable-adjusted analysis revealed significant correlations between fewer cerebral white matter lesions and higher green tea consumption, whereas no significant differences were found between green tea consumption and hippocampal or total brain volume. Regarding coffee consumption, no significant differences were observed in cerebral white matter lesions or hippocampal or total brain volumes. Hence, higher green tea consumption was associated with fewer cerebral white matter lesions, suggesting that it may be useful in preventing dementia.
UR - https://www.scopus.com/pages/publications/105010412691
UR - https://www.scopus.com/pages/publications/105010412691#tab=citedBy
U2 - 10.1038/s41538-024-00364-w
DO - 10.1038/s41538-024-00364-w
M3 - Article
AN - SCOPUS:105010412691
SN - 2396-8370
VL - 9
JO - npj Science of Food
JF - npj Science of Food
IS - 1
M1 - 2
ER -
SDG 3 すべての人に健康と福祉を