[Guideline of prevention and treatment for NSAIDs induced ulcer].

The guideline for peptic ulcer treatment was reported by Japanese Society of Gastroenterology in 2009. In the guideline, 23 clinical questions were chosen for NSAIDs induced ulcer. Nine questions out of them were related to the prevention, eight were low dose aspirin, three were COX-2 inhibitors and three were the treatment. The recommendations were made for these questions according to evidence-based medicine. In the recommendations, the grade of recommendation, the evidence level of literatures and the applications to Japanese medical insurance were mentioned.