Hemodynamic and echocardiographic evaluation of orthotopic heart transplantation with the modified bicaval anastomosis technique

Soichiro Kitamura, Takeshi Nakatani, Tomoko Kato, Masanobu Yanase, Junjiro Kobayashi, Hiroyuki Nakajima, Toshihiro Funatsu, Koichi Toda, Akiko Kada, Hitoshi Ogino, Toshikatsu Yagihara

研究成果: Article査読

15 被引用数 (Scopus)

抄録

Background: The purpose of this study was to evaluate the hemodynamic and echocardiographic function of hearts transplanted with the modified bicaval anastomosis technique (mBCAT). Methods and Results: Twenty consecutive patients (14 males, 6 females, age range 14-61 [41.3±11.5 years]) were evaluated 3.4±2.2 years after heart transplantation using the mBCAT. All patients were in status I on the waiting list, and 18 (90%) had had a left ventricular assist device. The donor age was 39±12 years. Triple immunosuppressive regimen and cardiac biopsy were routinely performed. There was no hospital mortality. One death occurred 4.2 years after the operation because of bone marrow dysplasia and infection. The 8-year survival was 89% (95% confidence interval: 0.43-0.98). All the hemodynamic variables returned to the normal range. Low right atrial pressure (3.2±1.5 mmHg) and low pulmonary wedge pressure (6.7±2.1 mmHg) were associated with an excellent cardiac index (3.9±0.7 L·min-1-m-2). Echocardiography revealed an excellent late peak velocity (52±19 cm/s) and an E/A ratio (1.4±0.6) of tricuspid flow. The grade (0-4) of tricuspid regurgitation averaged 1.5±0.8. Conclusions: Hemodynamic and echocardiographic results for mBCAT were excellent. The 8-year survival was 89% with all surviving patients in New York Heart Association class I. The mBCAT is easy to perform and further facilitates cardiac transplantation.

本文言語English
ページ(範囲)1235-1239
ページ数5
ジャーナルCirculation Journal
73
7
DOI
出版ステータスPublished - 07-2009
外部発表はい

All Science Journal Classification (ASJC) codes

  • 循環器および心血管医学

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