Hemodynamic responses in prefrontal cortex and personality characteristics in patients with bulimic disorders: a near-infrared spectroscopy study

Noriko Numata, Yoshiyuki Hirano, Chihiro Sutoh, Daisuke Matsuzawa, Kotaro Takeda, Rikukage Setsu, Eiji Shimizu, Michiko Nakazato

研究成果: Article

抜粋

Purpose: This study sought to identify the prefrontal cortex hemodynamic response that is dependent on cognitive performance in patients with bulimic disorders (BD), and investigate its association with personality characteristics. Methods: Nineteen female patients with BD and 23 healthy women were recruited. Their personality characteristics related to eating disorders were examined using a self-reporting questionnaire, namely the eating disorder inventory-2 (EDI-2). Cerebral blood flow response in the prefrontal cortex during the digit span backward task (DSBT) was measured using near-infrared spectroscopy (NIRS). Change in oxygenated hemoglobin concentration (ΔoxyHb), obtained using NIRS, were used as an index of brain activity. Further, the relationship between prefrontal cortical activity and personality characteristics was investigated in patients with BD. Results: The cognitive performance of patients with BD was significantly lower in the DSBT compared with healthy subjects. There was no difference between the groups in ΔoxyHb during the task. Task scores of patients with BD correlated with asceticism and perfectionism. Moreover, the asceticism score was negatively correlated with ΔoxyHb of the bilateral prefrontal cortex in patients with BD. Conclusion: The results suggest that cognitive performance and brain activity induced during DSBT might be affected by asceticism in BD patients. Level of evidence: III, case-control study.

元の言語English
ページ(範囲)59-67
ページ数9
ジャーナルEating and Weight Disorders
25
発行部数1
DOI
出版物ステータスPublished - 01-02-2020

All Science Journal Classification (ASJC) codes

  • Clinical Psychology
  • Psychiatry and Mental health

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