Histochemical demonstration of membranous localization of endothelial nitric oxide synthase in endothelial cells of the rat brain

Hidekazu Tomimoto, Ichiro Akiguchi, Hideaki Wakita, Sinichi Nakamura, Jun Kimura

研究成果: Article査読

22 被引用数 (Scopus)

抄録

We examined cellular and subcellular localization of endothelial nitric oxide synthase by using immunoelectron microscopy. The results showed that immunoreaction products were associated with membranous structure, likely the endoplasmic reticulum and cytoplasmic vesicles. These membranous localization of imunoreactivities at electron microscopic level corresponded to the perinuclear granular structures observed by light microscopic immunohistochemistry for endothelial nitric oxide synthase as well as NADPH diaphorase histochemistry.

本文言語English
ページ(範囲)107-110
ページ数4
ジャーナルBrain Research
667
1
DOI
出版ステータスPublished - 19-12-1994
外部発表はい

All Science Journal Classification (ASJC) codes

  • 神経科学(全般)
  • 分子生物学
  • 臨床神経学
  • 発生生物学

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