Histochemical demonstration of membranous localization of endothelial nitric oxide synthase in endothelial cells of the rat brain

Hidekazu Tomimoto; Ichiro Akiguchi; Hideaki Wakita; Sinichi Nakamura; Jun Kimura

doi:10.1016/0006-8993(94)91718-3

Histochemical demonstration of membranous localization of endothelial nitric oxide synthase in endothelial cells of the rat brain

Hidekazu Tomimoto
, Ichiro Akiguchi
, Hideaki Wakita
, Sinichi Nakamura
, Jun Kimura

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

22 被引用数 (Scopus)

抄録

We examined cellular and subcellular localization of endothelial nitric oxide synthase by using immunoelectron microscopy. The results showed that immunoreaction products were associated with membranous structure, likely the endoplasmic reticulum and cytoplasmic vesicles. These membranous localization of imunoreactivities at electron microscopic level corresponded to the perinuclear granular structures observed by light microscopic immunohistochemistry for endothelial nitric oxide synthase as well as NADPH diaphorase histochemistry.

本文言語	英語
ページ（範囲）	107-110
ページ数	4
ジャーナル	Brain Research
巻	667
号	1
DOI	https://doi.org/10.1016/0006-8993(94)91718-3
出版ステータス	出版済み - 19-12-1994
外部発表	はい

All Science Journal Classification (ASJC) codes

神経科学一般
分子生物学
臨床神経学
発生生物学

文献へのアクセス

10.1016/0006-8993(94)91718-3

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「Histochemical demonstration of membranous localization of endothelial nitric oxide synthase in endothelial cells of the rat brain」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル

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abstract = "We examined cellular and subcellular localization of endothelial nitric oxide synthase by using immunoelectron microscopy. The results showed that immunoreaction products were associated with membranous structure, likely the endoplasmic reticulum and cytoplasmic vesicles. These membranous localization of imunoreactivities at electron microscopic level corresponded to the perinuclear granular structures observed by light microscopic immunohistochemistry for endothelial nitric oxide synthase as well as NADPH diaphorase histochemistry.",

author = "Hidekazu Tomimoto and Ichiro Akiguchi and Hideaki Wakita and Sinichi Nakamura and Jun Kimura",

note = "Funding Information: Sclerosis and Peripheral Neuropathy from the Japanese Ministry of Health and Welfare and a grant from Kanae Foundation of Research for New Medicine (to H.T.). Funding Information: This work was supported by a Grand-in-Aid for Scientific Research on Priority Areas from the Ministry of Education, Grants-in-Aid for Amyotrophic Lateral",

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AU - Wakita, Hideaki

AU - Nakamura, Sinichi

AU - Kimura, Jun

N1 - Funding Information: Sclerosis and Peripheral Neuropathy from the Japanese Ministry of Health and Welfare and a grant from Kanae Foundation of Research for New Medicine (to H.T.). Funding Information: This work was supported by a Grand-in-Aid for Scientific Research on Priority Areas from the Ministry of Education, Grants-in-Aid for Amyotrophic Lateral

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