Homozygous TRPV1 315C Influences the Susceptibility to Functional Dyspepsia

Tomomitsu Tahara; Tomoyuki Shibata; Masakatsu Nakamura; Hiromi Yamashita; Daisuke Yoshioka; Ichiro Hirata; Tomiyasu Arisawa

doi:10.1097/MCG.0b013e3181b5745e

Homozygous TRPV1 315C Influences the Susceptibility to Functional Dyspepsia

Tomomitsu Tahara, Tomoyuki Shibata, Masakatsu Nakamura, Hiromi Yamashita, Daisuke Yoshioka, Ichiro Hirata, Tomiyasu Arisawa

医学部・消化器内科学・第１

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

54 被引用数 (Scopus)

抄録

Capsaicin/vanilloid (transient receptor potential vanilloid 1, (TRPV1) receptor has been shown to be expressed in gastrointestinal tract and play a role as a member of sensory ion channel superfamily. The G315C polymorphism affects the TRPV1 gene and alters its protein level. We aimed to investigate the effect of TRPV1 G315C polymorphism on functional dyspepsia (FD) in a Japanese population.

本文言語	英語
ページ（範囲）	e1-e7
ジャーナル	Journal of Clinical Gastroenterology
巻	44
号	1
DOI	https://doi.org/10.1097/MCG.0b013e3181b5745e
出版ステータス	出版済み - 01-2010

All Science Journal Classification (ASJC) codes

消化器病学

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10.1097/MCG.0b013e3181b5745e

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abstract = "Capsaicin/vanilloid (transient receptor potential vanilloid 1, (TRPV1) receptor has been shown to be expressed in gastrointestinal tract and play a role as a member of sensory ion channel superfamily. The G315C polymorphism affects the TRPV1 gene and alters its protein level. We aimed to investigate the effect of TRPV1 G315C polymorphism on functional dyspepsia (FD) in a Japanese population.",

author = "Tomomitsu Tahara and Tomoyuki Shibata and Masakatsu Nakamura and Hiromi Yamashita and Daisuke Yoshioka and Ichiro Hirata and Tomiyasu Arisawa",

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AU - Tahara, Tomomitsu

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AU - Nakamura, Masakatsu

AU - Yamashita, Hiromi

AU - Yoshioka, Daisuke

AU - Hirata, Ichiro

AU - Arisawa, Tomiyasu

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AB - Capsaicin/vanilloid (transient receptor potential vanilloid 1, (TRPV1) receptor has been shown to be expressed in gastrointestinal tract and play a role as a member of sensory ion channel superfamily. The G315C polymorphism affects the TRPV1 gene and alters its protein level. We aimed to investigate the effect of TRPV1 G315C polymorphism on functional dyspepsia (FD) in a Japanese population.

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SP - e1-e7

JO - Journal of Clinical Gastroenterology

JF - Journal of Clinical Gastroenterology

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Homozygous TRPV1 315C Influences the Susceptibility to Functional Dyspepsia

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