Hyper IgM syndrome and complement Clq deficiency in an individual with systemic lupus erythematosus-like disease

Ikuya Tsuge; Yasuto Kondo; Yoichi Nakajima; Noriko Nakagawa; Kohsuke Imai; Shigeaki Nonoyama; Koichi Oshima; Osamu Ohara; Michiyo Hatanaka; Etsuko Kitano; Hajime Kitamura; Atsuo Urisu

Hyper IgM syndrome and complement Clq deficiency in an individual with systemic lupus erythematosus-like disease

Ikuya Tsuge, Yasuto Kondo, Yoichi Nakajima, Noriko Nakagawa, Kohsuke Imai, Shigeaki Nonoyama, Koichi Oshima, Osamu Ohara, Michiyo Hatanaka, Etsuko Kitano, Hajime Kitamura, Atsuo Urisu

小児科学

研究成果: Article › 査読

7 被引用数 (Scopus)

抄録

Many immunedeficiency syndromes are associated with autoimmune disorders. We here report on a girl with a systemic lupus erythematosus-like disease who suffered from both hyperimmunoglobulin M syndrome (HIGMS) and C1q deficiency. Despite severe central nervous system-lupus like disease, probably due to C1q deficiency, kidney function was relatively spared. IgM autoantibody might play a protective role against lupus-glomerulonephritis.

本文言語	English
ページ（範囲）	558-560
ページ数	3
ジャーナル	Clinical and Experimental Rheumatology
巻	28
号	4
出版ステータス	Published - 01-12-2010

All Science Journal Classification (ASJC) codes

Rheumatology
Immunology and Allergy
Immunology

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引用スタイル

Tsuge, Ikuya ; Kondo, Yasuto ; Nakajima, Yoichi ; Nakagawa, Noriko ; Imai, Kohsuke ; Nonoyama, Shigeaki ; Oshima, Koichi ; Ohara, Osamu ; Hatanaka, Michiyo ; Kitano, Etsuko ; Kitamura, Hajime ; Urisu, Atsuo. / Hyper IgM syndrome and complement Clq deficiency in an individual with systemic lupus erythematosus-like disease. In: Clinical and Experimental Rheumatology. 2010 ; Vol. 28, No. 4. pp. 558-560.

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Hyper IgM syndrome and complement Clq deficiency in an individual with systemic lupus erythematosus-like disease. / Tsuge, Ikuya; Kondo, Yasuto ; Nakajima, Yoichi; Nakagawa, Noriko; Imai, Kohsuke; Nonoyama, Shigeaki; Oshima, Koichi; Ohara, Osamu; Hatanaka, Michiyo; Kitano, Etsuko; Kitamura, Hajime; Urisu, Atsuo.

In: Clinical and Experimental Rheumatology, Vol. 28, No. 4, 01.12.2010, p. 558-560.

研究成果: Article › 査読

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AU - Tsuge, Ikuya

AU - Kondo, Yasuto

AU - Nakajima, Yoichi

AU - Nakagawa, Noriko

AU - Imai, Kohsuke

AU - Nonoyama, Shigeaki

AU - Oshima, Koichi

AU - Ohara, Osamu

AU - Hatanaka, Michiyo

AU - Kitano, Etsuko

AU - Kitamura, Hajime

AU - Urisu, Atsuo

PY - 2010/12/1

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AB - Many immunedeficiency syndromes are associated with autoimmune disorders. We here report on a girl with a systemic lupus erythematosus-like disease who suffered from both hyperimmunoglobulin M syndrome (HIGMS) and C1q deficiency. Despite severe central nervous system-lupus like disease, probably due to C1q deficiency, kidney function was relatively spared. IgM autoantibody might play a protective role against lupus-glomerulonephritis.

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