抄録
Management of dementia and cognitive decline is a major issue in geriatrics. Since the average age of society is advancing and patients of dementia are increasing, it is important to remove risk factors of dementia and cognitive decline in order to maintain quality of life in the elderly and to save cost of medicine and care. While hypertension has been known to be a risk factor of cerebrovascular events and vascular dementia, recent studies show that midlife hypertension is also a risk factor of cognitive decline and Alzheimer's disease in late life. Clinical trials and retrospective observation studies also show that treatment of hypertension decreases the risk of Alzheimer's disease. These issues are also related with the consideration of vascular factors in Alzheimer's disease. The white matter lesion as a consequence of hypertension and its meaning in Alzheimer's disease are also discussed.
| 元の言語 | English |
|---|---|
| ページ（範囲） | 433-436 |
| ページ数 | 4 |
| ジャーナル | Japanese Journal of Geriatrics |
| 巻 | 44 |
| 発行部数 | 4 |
| DOI | |
| 出版物ステータス | Published - 01-07-2007 |
| 外部発表 | Yes |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
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Hypertension as a risk factor of dementia and cognitive decline in the elderly. / Takechi, Hajime.
：: Japanese Journal of Geriatrics, 巻 44, 番号 4, 01.07.2007, p. 433-436.研究成果: Article
TY - JOUR
T1 - Hypertension as a risk factor of dementia and cognitive decline in the elderly
AU - Takechi, Hajime
PY - 2007/7/1
Y1 - 2007/7/1
N2 - Management of dementia and cognitive decline is a major issue in geriatrics. Since the average age of society is advancing and patients of dementia are increasing, it is important to remove risk factors of dementia and cognitive decline in order to maintain quality of life in the elderly and to save cost of medicine and care. While hypertension has been known to be a risk factor of cerebrovascular events and vascular dementia, recent studies show that midlife hypertension is also a risk factor of cognitive decline and Alzheimer's disease in late life. Clinical trials and retrospective observation studies also show that treatment of hypertension decreases the risk of Alzheimer's disease. These issues are also related with the consideration of vascular factors in Alzheimer's disease. The white matter lesion as a consequence of hypertension and its meaning in Alzheimer's disease are also discussed.
AB - Management of dementia and cognitive decline is a major issue in geriatrics. Since the average age of society is advancing and patients of dementia are increasing, it is important to remove risk factors of dementia and cognitive decline in order to maintain quality of life in the elderly and to save cost of medicine and care. While hypertension has been known to be a risk factor of cerebrovascular events and vascular dementia, recent studies show that midlife hypertension is also a risk factor of cognitive decline and Alzheimer's disease in late life. Clinical trials and retrospective observation studies also show that treatment of hypertension decreases the risk of Alzheimer's disease. These issues are also related with the consideration of vascular factors in Alzheimer's disease. The white matter lesion as a consequence of hypertension and its meaning in Alzheimer's disease are also discussed.
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UR - http://www.scopus.com/inward/citedby.url?scp=34548314580&partnerID=8YFLogxK
U2 - 10.3143/geriatrics.44.433
DO - 10.3143/geriatrics.44.433
M3 - Article
C2 - 17827796
AN - SCOPUS:34548314580
VL - 44
SP - 433
EP - 436
JO - Japanese Journal of Geriatrics
JF - Japanese Journal of Geriatrics
SN - 0300-9173
IS - 4
ER -