Identification and characterization of a human G9P[23] rotavirus strain from a child with diarrhoea in Thailand: Evidence for porcine-to-human interspecies transmission

Satoshi Komoto, Ratana Tacharoenmuang, Ratigorn Guntapong, Tomihiko Ide, Phakapun Sinchai, Sompong Upachai, Saori Fukuda, Tetsushi Yoshikawa, Piyanit Tharmaphornpilas, Somchai Sangkitporn, Koki Taniguchi

研究成果: Article

4 引用 (Scopus)

抜粋

An unusual rotavirus strain with the G9P[23] genotype (RVA/Human-wt/THA/KKL-117/2014/G9P[23]) was identified in a stool specimen from a 10-month-old child hospitalized with severe diarrhoea. In this study, we sequenced and characterized the complete genome of strain KKL-117. On full-genomic analysis, strain KKL-117 was found to have the following genotype constellation: G9-P[23]-I5-R1-C1-M1-A8-N1-T1-E1-H1. The non-G/P genotype constellation of this strain (I5-R1-C1-M1-A8- N1-T1-E1-H1) is commonly shared with rotavirus strains from pigs. Furthermore, phylogenetic analysis indicated that each of the 11 genes of strain KKL-117 appeared to be of porcine origin. Our observations provide important insights into the dynamic interactions between human and porcine rotavirus strains.

元の言語English
ページ(範囲)532-538
ページ数7
ジャーナルJournal of General Virology
98
発行部数4
DOI
出版物ステータスPublished - 04-2017

All Science Journal Classification (ASJC) codes

  • Virology

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