Identification and transcriptional analysis of pseudorabies virus UL6 to UL12 genes

J・m Dijkstra, W. Fuchs, T. C. Mettenleiter, B. G. Klupp

研究成果: Article

22 引用 (Scopus)

抄録

We determined the nucleotide sequence of an 11059 bp fragment of the pseudorabies virus genome located in the right part of genomic BamHI fragment 3 and the adjacent part of BamHI fragment 6. Within this region eight open reading frames were identified whose deduced amino acid sequences exhibited homology to the UL6, UL7, UL8, UL8.5, UL9, UL10, UL11, and UL12 protein products of herpes simplex virus type 1. Transcriptional analyses indicated presence of 3'-coterminal mRNAs for genes UL8, UL8.5, and UL9 as well as for genes UL6 and UL7, respectively, while UL10 was represented by a very abundant unique transcript. Both gene arrangement and transcriptional organization within this region of the pseudorabies virus genome thus parallels the situation found in other alphaherpesviruses.

元の言語English
ページ(範囲)17-35
ページ数19
ジャーナルArchives of Virology
142
発行部数1
DOI
出版物ステータスPublished - 06-02-1997

Fingerprint

Suid Herpesvirus 1
Genome
Amino Acid Sequence Homology
Gene Order
Human Herpesvirus 1
Open Reading Frames
Genes
Messenger RNA
Proteins

All Science Journal Classification (ASJC) codes

  • Virology

これを引用

Dijkstra, J・m ; Fuchs, W. ; Mettenleiter, T. C. ; Klupp, B. G. / Identification and transcriptional analysis of pseudorabies virus UL6 to UL12 genes. :: Archives of Virology. 1997 ; 巻 142, 番号 1. pp. 17-35.
@article{085a9f4edae74442946d8525b4616b3b,
title = "Identification and transcriptional analysis of pseudorabies virus UL6 to UL12 genes",
abstract = "We determined the nucleotide sequence of an 11059 bp fragment of the pseudorabies virus genome located in the right part of genomic BamHI fragment 3 and the adjacent part of BamHI fragment 6. Within this region eight open reading frames were identified whose deduced amino acid sequences exhibited homology to the UL6, UL7, UL8, UL8.5, UL9, UL10, UL11, and UL12 protein products of herpes simplex virus type 1. Transcriptional analyses indicated presence of 3'-coterminal mRNAs for genes UL8, UL8.5, and UL9 as well as for genes UL6 and UL7, respectively, while UL10 was represented by a very abundant unique transcript. Both gene arrangement and transcriptional organization within this region of the pseudorabies virus genome thus parallels the situation found in other alphaherpesviruses.",
author = "J・m Dijkstra and W. Fuchs and Mettenleiter, {T. C.} and Klupp, {B. G.}",
year = "1997",
month = "2",
day = "6",
doi = "10.1007/s007050050056",
language = "English",
volume = "142",
pages = "17--35",
journal = "Archives of Virology",
issn = "0304-8608",
publisher = "Springer Wien",
number = "1",

}

Identification and transcriptional analysis of pseudorabies virus UL6 to UL12 genes. / Dijkstra, J・m; Fuchs, W.; Mettenleiter, T. C.; Klupp, B. G.

:: Archives of Virology, 巻 142, 番号 1, 06.02.1997, p. 17-35.

研究成果: Article

TY - JOUR

T1 - Identification and transcriptional analysis of pseudorabies virus UL6 to UL12 genes

AU - Dijkstra, J・m

AU - Fuchs, W.

AU - Mettenleiter, T. C.

AU - Klupp, B. G.

PY - 1997/2/6

Y1 - 1997/2/6

N2 - We determined the nucleotide sequence of an 11059 bp fragment of the pseudorabies virus genome located in the right part of genomic BamHI fragment 3 and the adjacent part of BamHI fragment 6. Within this region eight open reading frames were identified whose deduced amino acid sequences exhibited homology to the UL6, UL7, UL8, UL8.5, UL9, UL10, UL11, and UL12 protein products of herpes simplex virus type 1. Transcriptional analyses indicated presence of 3'-coterminal mRNAs for genes UL8, UL8.5, and UL9 as well as for genes UL6 and UL7, respectively, while UL10 was represented by a very abundant unique transcript. Both gene arrangement and transcriptional organization within this region of the pseudorabies virus genome thus parallels the situation found in other alphaherpesviruses.

AB - We determined the nucleotide sequence of an 11059 bp fragment of the pseudorabies virus genome located in the right part of genomic BamHI fragment 3 and the adjacent part of BamHI fragment 6. Within this region eight open reading frames were identified whose deduced amino acid sequences exhibited homology to the UL6, UL7, UL8, UL8.5, UL9, UL10, UL11, and UL12 protein products of herpes simplex virus type 1. Transcriptional analyses indicated presence of 3'-coterminal mRNAs for genes UL8, UL8.5, and UL9 as well as for genes UL6 and UL7, respectively, while UL10 was represented by a very abundant unique transcript. Both gene arrangement and transcriptional organization within this region of the pseudorabies virus genome thus parallels the situation found in other alphaherpesviruses.

UR - http://www.scopus.com/inward/record.url?scp=0031015226&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031015226&partnerID=8YFLogxK

U2 - 10.1007/s007050050056

DO - 10.1007/s007050050056

M3 - Article

VL - 142

SP - 17

EP - 35

JO - Archives of Virology

JF - Archives of Virology

SN - 0304-8608

IS - 1

ER -