TY - JOUR
T1 - Identification of a neuronal cell surface molecule, plexin, in mice
AU - Kameyama, Toshiki
AU - Murakami, Yasunori
AU - Suto, Fumikazu
AU - Kawakami, Atsushi
AU - Takagi, Shin
AU - Hirata, Tatsumi
AU - Fujisawa, Hajime
N1 - Funding Information:
This work was supported by grants from the Ministry of Education, Science and Culture, Japan, from the special coordination funds of the Science and Technology Agency of the Japanese Government, and was partly supported by Research Fellowships of the Japan Society for the Promotion of Science for Young Scientists (to T.K.).
PY - 1996/9/13
Y1 - 1996/9/13
N2 - We searched for mouse homologues of the cell adhesion protein plexin which was originally found in Xenopus, and obtained a cDNA encoding a plexin-like protein. We referred to this protein as mouse plexin 1. The overall amino acid identity between mouse plexin 1 and Xenopus plexin was 84%. As in the Xenopus plexin, the extracellular segment of mouse plexin 1 protein possessed three cysteine-rich domains which showed significant homology with the cysteine-rich domain of the c-Met proto-oncogene protein product (c-Met protein) and Met-like receptor protein tyrosine kinases. Northern blot analysis indicated that mouse plexin 1 was predominantly expressed in the brain.
AB - We searched for mouse homologues of the cell adhesion protein plexin which was originally found in Xenopus, and obtained a cDNA encoding a plexin-like protein. We referred to this protein as mouse plexin 1. The overall amino acid identity between mouse plexin 1 and Xenopus plexin was 84%. As in the Xenopus plexin, the extracellular segment of mouse plexin 1 protein possessed three cysteine-rich domains which showed significant homology with the cysteine-rich domain of the c-Met proto-oncogene protein product (c-Met protein) and Met-like receptor protein tyrosine kinases. Northern blot analysis indicated that mouse plexin 1 was predominantly expressed in the brain.
UR - https://www.scopus.com/pages/publications/0030582321
UR - https://www.scopus.com/pages/publications/0030582321#tab=citedBy
U2 - 10.1006/bbrc.1996.1388
DO - 10.1006/bbrc.1996.1388
M3 - Article
C2 - 8806667
AN - SCOPUS:0030582321
SN - 0006-291X
VL - 226
SP - 524
EP - 529
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 2
ER -