Identification of epilepsy-related genes by gene expression profiling in the hippocampus of genetically epileptic rat

Masaaki Arai, Shigeru Amano, Akihide Ryo, Akiyuki Hada, Toru Wakatsuki, Masahiro Shuda, Nobuo Kondoh, Mikio Yamamoto

研究成果: Article査読

9 被引用数 (Scopus)

抄録

Ihara epileptic rat (IER) is an animal model of temporal lobe epilepsy (TLE) with genetically programmed microdysgenesis in the hippocampal formation. The neuronal microdysgenesis is thought to be a cause for recurrent spontaneous seizures. To identify differentially expressed genes in the hippocampus of IER in comparison to control Wistar rat, we performed serial analysis of gene expression (SAGE). As many as 21 differentially expressed genes were identified.

本文言語English
ページ(範囲)147-151
ページ数5
ジャーナルMolecular Brain Research
118
1-2
DOI
出版ステータスPublished - 21-10-2003
外部発表はい

All Science Journal Classification (ASJC) codes

  • 分子生物学
  • 細胞および分子神経科学

フィンガープリント

「Identification of epilepsy-related genes by gene expression profiling in the hippocampus of genetically epileptic rat」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル