Idiopathic intracranial hypotension associated with decreased blood concentration of vitamin A

Kazunori Akaji, Masateru Katayama, Masachika Sagoh, Yuichi Hirose, Hideki Murakami

研究成果: Article

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We report a case of idiopathic intracranial hypotension, a clinically rare syndrome. A 28-year-old woman was admitted with orthostatic headaches associated with nausea secondary to intracranial hypotension. Lumbar puncture yielded an opening pressure of 4 cmH2O in the lateral recumbent position, and the spinal fluid protein concentration was 56 mg/dl. There was no history of lumbar puncture or clear history of head trauma before the onset of symptoms. Spinal and cranial MRI showed no evidence of CSF leakage, and there was diffuse meningeal enhancement following gadolinium infusion. Cranial MRI showed no evidence of brain displacement due to low CSF pressure, such as tonsillar herniation. Radioisotope cisternography (RIC) showed rapid accumulation of isotope wihin the bladder and early disapperance of radioactivity from the head. About 2 months later the headaches resolved spontaneously, and repeated lumbar puncture yielded opening pressure elevation to 10.5 cmH2O with a decrease in protein concentration to 28 mg/dl. The abnormal MRI and RIC findings had become normal. On the other hand, the patient had a low blood concentration of vitamin A, which is thought to play some role in the production of CSF. The results of RIC suggested that the patient may have become symptomatic because of undetectable CSF leakage or hyperabsorption, but diminished production of CSF due to lower blood vitamin A concentrations may also have been a factor predisposing to this syndrome.

元の言語English
ページ(範囲)x4-1139
ジャーナルBrain and Nerve
48
発行部数12
出版物ステータスPublished - 01-12-1996

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Intracranial Hypotension
Spinal Puncture
Vitamin A
Radioisotopes
Pressure
Headache
Encephalocele
Gadolinium
Craniocerebral Trauma
Isotopes
Causality
Radioactivity
Nausea
Urinary Bladder
Proteins
Head
Brain

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

これを引用

Akaji, Kazunori ; Katayama, Masateru ; Sagoh, Masachika ; Hirose, Yuichi ; Murakami, Hideki. / Idiopathic intracranial hypotension associated with decreased blood concentration of vitamin A. :: Brain and Nerve. 1996 ; 巻 48, 番号 12. pp. x4-1139.
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Akaji, K, Katayama, M, Sagoh, M, Hirose, Y & Murakami, H 1996, 'Idiopathic intracranial hypotension associated with decreased blood concentration of vitamin A', Brain and Nerve, 巻. 48, 番号 12, pp. x4-1139.

Idiopathic intracranial hypotension associated with decreased blood concentration of vitamin A. / Akaji, Kazunori; Katayama, Masateru; Sagoh, Masachika; Hirose, Yuichi; Murakami, Hideki.

:: Brain and Nerve, 巻 48, 番号 12, 01.12.1996, p. x4-1139.

研究成果: Article

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