IgG antibodies to HPV16, 52, 58 and 6 L1-capsids and spontaneous regression of cervical intraepithelial neoplasia

Koji Matsumoto, Toshiharu Yasugi, Akinori Oki, Takuma Fujii, Chisato Nagata, Souei Sekiya, Hiroshi Hoshiai, Yuji Taketani, Tadahito Kanda, Takashi Kawana, Hiroyuki Yoshikawa

研究成果: Article

17 引用 (Scopus)

抄録

To identify the predictive markers for spontaneous regression of cervical intraepithelial neoplasia (CIN), we examined whether IgG antibody responses to common human papillomavirus (HPV) L1-capsids correlate with CIN regression. In a cohort study, a total of 116 Japanese women with CIN grade I/II were tested for cervical HPV DNA and serum IgG antibodies to HPV16/52/58/6 L1-capsids. Our data suggest that baseline IgG reactivities to HPV L1-capsids do not serve as a predictive marker of CIN regression, in contrast to histological CIN grades and HPV DNA status.

元の言語English
ページ(範囲)309-313
ページ数5
ジャーナルCancer Letters
231
発行部数2
DOI
出版物ステータスPublished - 18-01-2006
外部発表Yes

Fingerprint

Cervical Intraepithelial Neoplasia
Capsid
Immunoglobulin G
Antibodies
DNA
Antibody Formation
Cohort Studies
Serum

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

これを引用

Matsumoto, Koji ; Yasugi, Toshiharu ; Oki, Akinori ; Fujii, Takuma ; Nagata, Chisato ; Sekiya, Souei ; Hoshiai, Hiroshi ; Taketani, Yuji ; Kanda, Tadahito ; Kawana, Takashi ; Yoshikawa, Hiroyuki. / IgG antibodies to HPV16, 52, 58 and 6 L1-capsids and spontaneous regression of cervical intraepithelial neoplasia. :: Cancer Letters. 2006 ; 巻 231, 番号 2. pp. 309-313.
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abstract = "To identify the predictive markers for spontaneous regression of cervical intraepithelial neoplasia (CIN), we examined whether IgG antibody responses to common human papillomavirus (HPV) L1-capsids correlate with CIN regression. In a cohort study, a total of 116 Japanese women with CIN grade I/II were tested for cervical HPV DNA and serum IgG antibodies to HPV16/52/58/6 L1-capsids. Our data suggest that baseline IgG reactivities to HPV L1-capsids do not serve as a predictive marker of CIN regression, in contrast to histological CIN grades and HPV DNA status.",
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Matsumoto, K, Yasugi, T, Oki, A, Fujii, T, Nagata, C, Sekiya, S, Hoshiai, H, Taketani, Y, Kanda, T, Kawana, T & Yoshikawa, H 2006, 'IgG antibodies to HPV16, 52, 58 and 6 L1-capsids and spontaneous regression of cervical intraepithelial neoplasia', Cancer Letters, 巻. 231, 番号 2, pp. 309-313. https://doi.org/10.1016/j.canlet.2005.02.023

IgG antibodies to HPV16, 52, 58 and 6 L1-capsids and spontaneous regression of cervical intraepithelial neoplasia. / Matsumoto, Koji; Yasugi, Toshiharu; Oki, Akinori; Fujii, Takuma; Nagata, Chisato; Sekiya, Souei; Hoshiai, Hiroshi; Taketani, Yuji; Kanda, Tadahito; Kawana, Takashi; Yoshikawa, Hiroyuki.

:: Cancer Letters, 巻 231, 番号 2, 18.01.2006, p. 309-313.

研究成果: Article

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T1 - IgG antibodies to HPV16, 52, 58 and 6 L1-capsids and spontaneous regression of cervical intraepithelial neoplasia

AU - Matsumoto, Koji

AU - Yasugi, Toshiharu

AU - Oki, Akinori

AU - Fujii, Takuma

AU - Nagata, Chisato

AU - Sekiya, Souei

AU - Hoshiai, Hiroshi

AU - Taketani, Yuji

AU - Kanda, Tadahito

AU - Kawana, Takashi

AU - Yoshikawa, Hiroyuki

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