Immune response to gangliosides in a case of Guillain - Barre syndrome after varicella

T. Yoshikawa, K. Suzuki, S. Suga, E. Miyata, H. Yamamoto, T. Hosokawa, T. Kumagai, Y. Asano

研究成果: Article

15 引用 (Scopus)

抜粋

An 8 year old girl was admitted to hospital with the typical clinical features of Guillain-Barre syndrome (GBS) after recovering from varicella. Onset of the disease was just two weeks after the onset of varicella in her young sister. Examination of cerebrospinal fluid and nerve conduction studies showed typical findings of GBS. Although serum from both the patient and sister were analysed for autoantibodies to gangliosides and myelin P0 protein, IgM anti-GM1 antibody and anti-GD1b antibody were only detected in the patient. HLA DR haplotypes were quite different between the two subjects. This suggests that these autoantibodles may play an important role in the pathogenesis of GBS after varicella zoster virus infection.

元の言語English
ページ(範囲)172-173
ページ数2
ジャーナルArchives of Disease in Childhood
83
発行部数2
DOI
出版物ステータスPublished - 14-09-2000

    フィンガープリント

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

これを引用

Yoshikawa, T., Suzuki, K., Suga, S., Miyata, E., Yamamoto, H., Hosokawa, T., Kumagai, T., & Asano, Y. (2000). Immune response to gangliosides in a case of Guillain - Barre syndrome after varicella. Archives of Disease in Childhood, 83(2), 172-173. https://doi.org/10.1136/adc.83.2.172