Immunohistochemical Studies of Chromogranins (A and C) in Pituitary Adenomas

K. Oda, K. Inada, R. Y. Osamura

研究成果: Article査読

5 被引用数 (Scopus)

抄録

Expression of Chromogranin A and C was examined immunohistochemically on 4S surgically obtained pituitary adenomas. Positive rate of chromogranin A was 40.0% and chromogranin C was positive in 8.0% of 4S pituitary adenomas. Chromogranin A was expressed frequently in adenomas in which at least one of the FSH alpha, FSH beta, LH beta and TSH beta subunits was positive. It also expressed frequently in non-functioning adenomas. The positive rate of chromogranin A was low in GH or PRL positive adenomas. These findings suggest that chromogranin could be a parameter of the functional differentiation of the pituitary adenomas.

本文言語English
ページ(範囲)626-628
ページ数3
ジャーナルPathology Research and Practice
187
5
DOI
出版ステータスPublished - 1991
外部発表はい

All Science Journal Classification (ASJC) codes

  • 病理学および法医学
  • 細胞生物学

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