Impact of post-dilatation on longitudinal stent elongation: An in vitro study

Takuya Sumi, Hideki Ishii, Akihito Tanaka, Susumu Suzuki, Hiroki Kojima, Naoki Iwakawa, Toshijiro Aoki, Kenshi Hirayama, Takayuki Mitsuda, Kazuhiro Harada, Yosuke Negishi, Tomoyuki Ota, Kenji Kada, Toyoaki Murohara

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Objectives: To evaluate whether balloon inflation for post-dilatation causes longitudinal stent deformation (LSD). Methods and results: Two stents, sized 2.5 mm × 28 mm and 3.5 mm × 28 mm (Nobori ® , biodegradable polymer biolimus-eluting stent; Ultimaster ® , biodegradable polymer sirolimus-eluting stent; Terumo Co., Tokyo, Japan), were deployed at nominal pressure in straight and tapered silicon vessel models. Then, post-dilatation was performed in two ways: dilatation from the distal (D-P group) or proximal (P-D group) side of the stent. Microscopic findings showed that the stents were elongated during every step of the procedure regardless of the post-dilatation method and type of vessel model. The D-P group showed linear elongation during each step of post-dilatation (straight model: 28.7 ± 0.3 mm vs. 29.9 ± 0.3 mm, p = 0.002; tapered model: 28.0 ± 0.1 mm vs. 29.9 ± 0.1 mm, p < 0.001). In contrast, in the P-D group, the most significant change was observed in the first step of post-dilatation and only slight changes were observed thereafter (straight model: 28.6 ± 0.1 mm vs. 29.5 ± 0.1 mm, p < 0.001; tapered model: 28.2 ± 0.1 mm vs. 29.5 ± 0.1 mm, p < 0.001). Optical frequency domain imaging analysis showed that the frequency of stent strut malapposition was positively correlated with the percentage change in stent length (r = 0.74, p < 0.0001). Conclusion: LSD was observed during every step of post-dilatation in both the straight and tapered vessel models. However, some differences were observed between the D-P and P-D groups. Minimizing stent strut malapposition may reduce the risk of LSD.

本文言語English
ページ(範囲)464-470
ページ数7
ジャーナルJournal of cardiology
71
5
DOI
出版ステータスPublished - 05-2018
外部発表はい

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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