In vivo pH monitoring using boron doped diamond microelectrode and silver needles: Application to stomach disorder diagnosis

Stéphane Fierro, Ryo Seishima, Osamu Nagano, Hideyuki Saya, Yasuaki Einaga

研究成果: Article査読

28 被引用数 (Scopus)

抄録

This study presents the in vivo electrochemical monitoring of pH using boron doped diamond (BDD) microelectrode and silver needles for potential application in medical diagnosis. Accurate calibration curve for pH determination were obtained through in vitro electrochemical measurements. The increase induced in stomach pH by treatment with pantoprazole was used to demonstrate that it is possible to monitor the pH in vivo using the simple and noninvasive system proposed herein. Using the results of the in vivo and in vitro experiments, a quantitative analysis of the increase in stomach pH is also presented. It is proposed that the catheter-free pH monitoring system presented in this study could be potentially employed in any biological environment.

本文言語English
論文番号3257
ジャーナルScientific reports
3
DOI
出版ステータスPublished - 2013
外部発表はい

All Science Journal Classification (ASJC) codes

  • General

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