Increase in electrocardiographic R-waves after revascularization in patients with acute myocardial infarction

Satoshi Isobe, Yasuo Takada, Akitada Ando, Satoru Ohshima, Kiyoyasu Yamada, Mamoru Nanasato, Kazumasa Unno, Takuo Ogawa, Takahisa Kondo, Hideo Izawa, Yasuya Inden, Makoto Hirai, Toyoaki Murohara

研究成果: Article査読

7 被引用数 (Scopus)

抄録

Background: The physiological mechanism of the increase in the electrocardiographic (ECG) R-wave voltage after revascularization in patients with acute myocardial infarction (MI) needs to be elucidated. Methods and Results: One hundred and thirty-eight MI patients (83: anterior MI, 45: inferior MI, 10: lateral MI) underwent ECG and echocardiography in both the acute and subacute phases after emergency revascularization, as well as a resting thallium-201/iodine-123 15-p-iodophenyl-3-(R,S)-methyl pentadecanoic acid myocardial scintigraphy in the acute phase. The total sum of the R-wave voltage (ΣR) was calculated over multiple leads on ECG for each infarcted lesion. Scintigraphic defect on each tracer was expressed as the percentage (%) defect of the total left ventricular (LV) myocardium. The % defect-discordance on both images in the acute phase and the % increase in ΣR and the absolute increase in LV ejection fraction from the acute to the subacute phase (ΔEF) were also calculated. The ΣR in the subacute phase was significantly greater than that in the acute phase (p<0.0001). The % increase in ΣR significantly correlated with the ΔEF (r=0.57, p<0.0001). The % increase in ΣR also correlated with the % defect-discordance (r=0.68, p<0.0001). Conclusions: The increase in the ECG R-wave voltage reflects not only the improvement in myocardial perfusion but also the presence of salvaged myocardium after revascularization in acute MI patients.

本文言語English
ページ(範囲)1385-1391
ページ数7
ジャーナルCirculation Journal
70
11
DOI
出版ステータスPublished - 2006
外部発表はい

All Science Journal Classification (ASJC) codes

  • 循環器および心血管医学

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