Infections with organisms producing extended-spectrum β-lactamase

David L. Paterson, Yohei Doi

研究成果: Chapter

抄録

Extended-spectrum β-lactamases (ESBL) are enzymes produced by a variety of Gram-negative bacilli, which confer reduced susceptibility to third-generation cephalosporins and aztreonam. Resistance to other antibiotic classes (such as aminoglycosides or fluoroquinolones) is also frequently observed in ESBL-producing organisms. Outbreaks of hospital-acquired infection with ESBL-producing organisms were recognized more than 20 years ago. Acquisition in nursing homes and other health care facilities was also noted. In more recent times, community-onset infections, sometimes in patients without health care contact, have been widely observed. The origins of community-acquired infection with ESBL-producing organisms is an area deserving much future study.

本文言語English
ホスト出版物のタイトルAntimicrobial Resistance
出版社S. Karger AG
ページ21-34
ページ数14
6
ISBN(電子版)9783805593243
ISBN(印刷版)9783805593236
DOI
出版ステータスPublished - 17-03-2010
外部発表はい

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Immunology and Microbiology(all)

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