Inhibition of Helicobacter pylori motility by (+)-syringaresinol from unripe Japanese apricot

Mitsuo Miyazawa, Hirotoshi Utsunomiya, Ken Ichi Inada, Tomoki Yamada, Yoshiharu Okuno, Harunari Tanaka, Masae Tatematsu

研究成果: Article査読

41 被引用数 (Scopus)

抄録

A methanol extract from unripe Japanese apricot showed inhibitory activity of Helicobacter pylori motility. Inhibitory compound 1 was isolated and identified as (+)-syringaresinol (1) by spectoroscopic means. (+)-Syringaresinol (1) inhibited ≥90% of the H. pylori motility at a concentration of 500 μg/ml and the IC50 value was 50 μg/ml.

本文言語English
ページ(範囲)172-173
ページ数2
ジャーナルBiological and Pharmaceutical Bulletin
29
1
DOI
出版ステータスPublished - 01-2006

All Science Journal Classification (ASJC) codes

  • 薬理学
  • 薬科学

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