Intravenous immunoglobulin therapy in proximal diabetic neuropathy

Yuichi Kawagashira, Hirohisa Watanabe, Yumiko Oki, Masahiro Iijima, Haruki Koike, Naoki Hattori, Masahisa Katsuno, Fumiaki Tanaka, Gen Sobue

研究成果: ジャーナルへの寄稿学術論文査読

2 被引用数 (Scopus)


A 57-year-old man with type 2 diabetes mellitus for 10 years showed progressive loss of muscle strength in both legs, pain and muscle atrophy in the femoral region and significant weight loss. On admission, he could not stand alone and used a wheelchair. He also complained of severe pain in the lower extremities. He was diagnosed with proximal diabetic neuropathy (PDN) by characteristic clinical and electrophysiological features. Intravenous immunoglobulin therapy (IVIg 0.4 g/kgx5 days) markedly reduced the severe pain and muscle weakness in the legs. Eventually, pain assessed by the Visual Analogue Scale was relieved by 80% and muscle strength was also well recovered, thereby enabling the patient to walk with a cane. The present case suggests that IVIg therapy may be effective for the relief of pain in PDN.

ジャーナルBMJ Case Reports
出版ステータス出版済み - 23-01-2009

All Science Journal Classification (ASJC) codes

  • 医学一般


「Intravenous immunoglobulin therapy in proximal diabetic neuropathy」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。