Intravenous immunoglobulin therapy markedly ameliorates muscle weakness ana severe pain in proximal diabetic neuropathy

Y. Kawagashira, H. Watanabe, Y. Oki, M. Iijima, H. Koike, N. Hattori, M. Katsuno, F. Tanaka, G. Sobue

研究成果: ジャーナルへの寄稿学術論文査読

20 被引用数 (Scopus)

抄録

A 57-year-old man with type 2 diabetes mellitus for 10 years showed progressive loss of muscle strength in both legs, pain and muscle atrophy in the femoral region and significant weight loss. On admission, he could not stand alone and used a wheelchair. He also complained of severe pain in the lower extremities. He was diagnosed with proximal diabetic neuropathy (PDN) by characteristic clinical and electrophysiological features. Intravenous immunoglobulin therapy (IVIg 0.4 g/kg x 5 days) markedly reduced the severe pain and muscle weakness in the legs. Eventually, pain assessed by the Visual Analogue Scale was relieved by 80% and muscle strength was also well recovered, thereby enabling the patient to walk with a cane. The present case suggests that IVIg therapy may be effective for the relief of pain in PDN.

本文言語英語
ページ(範囲)899-901
ページ数3
ジャーナルJournal of Neurology, Neurosurgery and Psychiatry
78
8
DOI
出版ステータス出版済み - 08-2007
外部発表はい

All Science Journal Classification (ASJC) codes

  • 外科
  • 臨床神経学
  • 精神医学および精神衛生

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