Inverse association between diabetes and aortic dilatation in patients with advanced coronary artery disease

Akihito Tanaka, Hideki Ishii, Hideki Oshima, Yuji Narita, Akio Kodama, Susumu Suzuki, Kimihiro Komori, Akihiko Usui, Toyoaki Murohara

研究成果: ジャーナルへの寄稿学術論文査読

14 被引用数 (Scopus)

抄録

Background: A negative association between diabetes and abdominal aortic aneurysm has recently been reported. The purpose of this study was to assess the relationship between diabetes and aortic diameter, including non-aneurysmal aortic diameter, in patients with advanced coronary artery disease. Methods: We identified 351 consecutive patients who had undergone coronary artery bypass graft surgery. The patients were divided into two groups: those with diabetes mellitus (DM) (DM+ group; n=180), and those without DM (DM- group; n=171). Infrarenal and ascending aortic diameters were measured by preoperative computed tomography and corrected for body surface area. Results: Infrarenal and ascending aortic diameters were significantly shorter in the DM+ group than in the DM- group (21.3±5.0mm vs. 24.7±9.8mm, p<0.001 and 36.0±4.4mm vs. 37.8±5.5mm, p=0.001, respectively). The rates of infrarenal aortic diameter ≥30mm and ascending aortic diameter ≥40mm were significantly lower in the DM+ group than in the DM- group (3.5% vs. 13.3%, p=0.003 and 14.2% vs. 24.1%, p=0.025, respectively). Multivariate models demonstrated diabetes to be an independent predictor of both infrarenal and ascending aortic diameters even after correction for body surface area. Conclusion: Our findings indicated an inverse association between diabetes and aortic dilatation of both the infrarenal and ascending aorta in patients with advanced coronary artery disease.

本文言語英語
ページ(範囲)123-127
ページ数5
ジャーナルAtherosclerosis
242
1
DOI
出版ステータス出版済み - 01-09-2015

All Science Journal Classification (ASJC) codes

  • 循環器および心血管医学

フィンガープリント

「Inverse association between diabetes and aortic dilatation in patients with advanced coronary artery disease」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル