抄録
Addition of platelet-derived growth factor (PDGF) to quiescent cultures of Swiss 3T3 fibroblasts rapidly increased the cytoplasmic free Ca2+ concentrations and afterwards the c-myc mRNA levels. The concentrations of PDGF needed for both reactions were roughly the same. Moreover, the Ca2+ ionophores, A23187 and ionomycin, mimicked the actions of PDGF and increased the c-myc mRNA levels. These results suggest that Ca2+ may be involved in the regulation of PDGF-induced expression of the c-myc gene.
本文言語 | 英語 |
---|---|
ページ(範囲) | 43-46 |
ページ数 | 4 |
ジャーナル | FEBS Letters |
巻 | 187 |
号 | 1 |
DOI | |
出版ステータス | 出版済み - 22-07-1985 |
外部発表 | はい |
All Science Journal Classification (ASJC) codes
- 生物理学
- 構造生物学
- 生化学
- 分子生物学
- 遺伝学
- 細胞生物学