Late mortality and morbidity in elderly patients with mechanical heart valves

Sadanari Sawaki, Akihiko Usui, Tomonobu Abe, Masaharu Yoshikawa, Toshiaki Akita, Yuichi Ueda

研究成果: Article査読

5 被引用数 (Scopus)


A retrospective study was performed in patients under and over 65 years old implanted with a mechanical valve, to compare late mortality and morbidity. Of 381 patients who underwent mechanical valve replacement at Nagoya University in the 1990s, 357 (11 hospital deaths and 13 lost to follow-up; 96.4% follow-up rate) were followed up for 7.9 ± 3.3 years (2,811 patient-years). They were divided into two groups either side of 65 years of age at operation. The young and elderly patient groups contained 275 and 82 patients, respectively. The survival rate in the young group was 96.1% (95% confidence interval, 93.7%-98.5%) at 5 years and 92.0% (95% confidence interval, 88.3%-95.7%) at 10 years, which was significantly better than 88.0% (95% confidence interval, 80.6%-95.4%) at 5 years and 73.8% (95% confidence interval, 66.2%-85.4%) at 10 years in the elderly group. The two groups did not differ significantly in the incidence of thromboembolic events, bleeding events, endocarditis, or reoperation. We are also encouraged by the fact that mechanical valves are not a risk factor for late mortality or morbidity, even in elderly patients.

ジャーナルAsian Cardiovascular and Thoracic Annals
出版ステータスPublished - 06-2006

All Science Journal Classification (ASJC) codes

  • 外科
  • 呼吸器内科
  • 循環器および心血管医学


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