Late recurrence of gastric carcinoma 15 years after surgery

Nobuhiko Ogasawara, Yu Ohkura, Masaki Ueno, Shusuke Haruta, Atsuhito Nakayama, Takatsugu Fujii, Aya Honda, Tsuyoshi Tanaka, Harushi Udagawa

研究成果: Article査読


A 70-year-old man who had undergone total gastrectomy 15 years ago for mucinous gastric carcinoma on the lesser curvature of the cardia, visited our hospital complaining of cough. Chest X-ray showed a right hilar shadow and an infiltrative shadow in the left middle lung field, which was not seen in the previous year. Whole-body positron emission tomography-computed tomography (CT) revealed abnormal uptake in the irregular consolidation of the left lung, enlarged right hilar lymph nodes, and a mass lesion on the right adrenal gland. Advanced primary lung adenocarcinoma with multi-organ metastasis was suspected and a CT-guided percutaneous lung biopsy was performed. Histopathological examination showed immunostaining patterns in complete accordance with those of the resected specimen of stomach, and the diagnosis of late recurrence of gastric carcinoma was confirmed. Pulmonary metastasis might have occurred as a direct hematogenous metastasis rather than through the liver. He achieved 31 months survival after the diagnosis receiving some sequences of chemotherapy. Late recurrence over 10 years after gastrectomy is extremely rare and significant predictive factors of late recurrence are not known. We hope that this case will help in detecting significant factors predictive of late recurrence after gastrectomy for gastric carcinoma.

ジャーナルClinical Journal of Gastroenterology
出版ステータスPublished - 01-10-2020

All Science Journal Classification (ASJC) codes

  • 消化器病学


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