Left ventricular assist device-associated endocarditis involving multiple clones of Staphylococcus aureus with distinct antimicrobial susceptibility patterns

Sohei Harada, Kotaro Aoki, Koh Okamoto, Osamu Kinoshita, Kan Nawata, Yoshikazu Ishii, Kazuhiro Tateda, Masakazu Sasaki, Tomoo Saga, Yohei Doi, Hiroshi Yotsuyanagi, Kyoji Moriya, Minoru Ono

研究成果: Article

抄録

The case of a patient with left ventricular assist device (LVAD)-associated endocarditis involving multiple clones of Staphylococcus aureus is presented. Different clones with distinct colony morphology were identified from blood cultures collected on the same day and showed diverse antimicrobial resistance patterns. In addition, a difference in antimicrobial susceptibility was observed even within an identical clone recovered 400 days apart due to the loss of SCCmec for methicillin and modification of the 23S rRNA target site for linezolid during a long-term treatment course.

元の言語English
ページ(範囲)44-47
ページ数4
ジャーナルInternational Journal of Infectious Diseases
84
DOI
出版物ステータスPublished - 01-07-2019

Fingerprint

Heart-Assist Devices
Endocarditis
Staphylococcus aureus
Linezolid
Clone Cells
Methicillin
Therapeutics

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

これを引用

Harada, Sohei ; Aoki, Kotaro ; Okamoto, Koh ; Kinoshita, Osamu ; Nawata, Kan ; Ishii, Yoshikazu ; Tateda, Kazuhiro ; Sasaki, Masakazu ; Saga, Tomoo ; Doi, Yohei ; Yotsuyanagi, Hiroshi ; Moriya, Kyoji ; Ono, Minoru. / Left ventricular assist device-associated endocarditis involving multiple clones of Staphylococcus aureus with distinct antimicrobial susceptibility patterns. :: International Journal of Infectious Diseases. 2019 ; 巻 84. pp. 44-47.
@article{eb1d241812cb4fbe90acfbde216190e6,
title = "Left ventricular assist device-associated endocarditis involving multiple clones of Staphylococcus aureus with distinct antimicrobial susceptibility patterns",
abstract = "The case of a patient with left ventricular assist device (LVAD)-associated endocarditis involving multiple clones of Staphylococcus aureus is presented. Different clones with distinct colony morphology were identified from blood cultures collected on the same day and showed diverse antimicrobial resistance patterns. In addition, a difference in antimicrobial susceptibility was observed even within an identical clone recovered 400 days apart due to the loss of SCCmec for methicillin and modification of the 23S rRNA target site for linezolid during a long-term treatment course.",
author = "Sohei Harada and Kotaro Aoki and Koh Okamoto and Osamu Kinoshita and Kan Nawata and Yoshikazu Ishii and Kazuhiro Tateda and Masakazu Sasaki and Tomoo Saga and Yohei Doi and Hiroshi Yotsuyanagi and Kyoji Moriya and Minoru Ono",
year = "2019",
month = "7",
day = "1",
doi = "10.1016/j.ijid.2019.05.001",
language = "English",
volume = "84",
pages = "44--47",
journal = "International Journal of Infectious Diseases",
issn = "1201-9712",
publisher = "Elsevier",

}

Left ventricular assist device-associated endocarditis involving multiple clones of Staphylococcus aureus with distinct antimicrobial susceptibility patterns. / Harada, Sohei; Aoki, Kotaro; Okamoto, Koh; Kinoshita, Osamu; Nawata, Kan; Ishii, Yoshikazu; Tateda, Kazuhiro; Sasaki, Masakazu; Saga, Tomoo; Doi, Yohei; Yotsuyanagi, Hiroshi; Moriya, Kyoji; Ono, Minoru.

:: International Journal of Infectious Diseases, 巻 84, 01.07.2019, p. 44-47.

研究成果: Article

TY - JOUR

T1 - Left ventricular assist device-associated endocarditis involving multiple clones of Staphylococcus aureus with distinct antimicrobial susceptibility patterns

AU - Harada, Sohei

AU - Aoki, Kotaro

AU - Okamoto, Koh

AU - Kinoshita, Osamu

AU - Nawata, Kan

AU - Ishii, Yoshikazu

AU - Tateda, Kazuhiro

AU - Sasaki, Masakazu

AU - Saga, Tomoo

AU - Doi, Yohei

AU - Yotsuyanagi, Hiroshi

AU - Moriya, Kyoji

AU - Ono, Minoru

PY - 2019/7/1

Y1 - 2019/7/1

N2 - The case of a patient with left ventricular assist device (LVAD)-associated endocarditis involving multiple clones of Staphylococcus aureus is presented. Different clones with distinct colony morphology were identified from blood cultures collected on the same day and showed diverse antimicrobial resistance patterns. In addition, a difference in antimicrobial susceptibility was observed even within an identical clone recovered 400 days apart due to the loss of SCCmec for methicillin and modification of the 23S rRNA target site for linezolid during a long-term treatment course.

AB - The case of a patient with left ventricular assist device (LVAD)-associated endocarditis involving multiple clones of Staphylococcus aureus is presented. Different clones with distinct colony morphology were identified from blood cultures collected on the same day and showed diverse antimicrobial resistance patterns. In addition, a difference in antimicrobial susceptibility was observed even within an identical clone recovered 400 days apart due to the loss of SCCmec for methicillin and modification of the 23S rRNA target site for linezolid during a long-term treatment course.

UR - http://www.scopus.com/inward/record.url?scp=85065861307&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85065861307&partnerID=8YFLogxK

U2 - 10.1016/j.ijid.2019.05.001

DO - 10.1016/j.ijid.2019.05.001

M3 - Article

C2 - 31075509

AN - SCOPUS:85065861307

VL - 84

SP - 44

EP - 47

JO - International Journal of Infectious Diseases

JF - International Journal of Infectious Diseases

SN - 1201-9712

ER -