Left ventricular hypertrophy and proteinuria in patients with essential hypertension in Andkhoy, Afghanistan

Mohammad Shoaib Hamrah, Mohammad Hassan Hamrah, Hideki Ishii, Susumu Suzuki, Mohammad Hussain Hamrah, Ahmad Edris Hamrah, Ahmad Elias Dahi, Maimaiti Yisireyili, Naoaki Kano, Kyosuke Takeshita, Mohammad Hashem Hamrah, Junichi Sakamoto, Toyoaki Murohara

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Left ventricular hypertrophy (LVH) and proteinuria are known as independent predictors of cardiovascular death in hypertension. However, LVH and its association with proteinuria have not been investigated in adult hypertensive patients in Afghanistan. The objective of this research was to determine the prevalence of LVH and the correlation between LVH and proteinuria among the Afghan adult hypertensive population visiting an outpatient clinic in Afghanistan. We retrospectively evaluated 789 hypertensive patients (mean age is 56 years and 46% were men) who visited the clinic between December 2014 and August 2016. Patient characteristics and laboratory and clinical findings were recorded. The rate of LVH among hypertensive patients was 54.4%. Patients with proteinuria had a significantly higher LVH percentage compared to those without proteinuria (73.2% versus 55.8%; P<0.001). There was a significant correlation between LVH and proteinuria among hypertensive patients (r=0.182, P<0.001). Based on a multivariate regression analysis, age (odds ratio [OR], 1.04; 95% confidence interval [CI], 1.02-1.05), proteinuria (OR, 1.69; 95% CI, 1.19-2.41), and female sex (OR, 0.09; 95% CI, 0.06-0.13) were significant factors. In conclusion, the prevalence of LVH was more than 50% in the Afghan adult hypertensive population. This study indicates that there is a significant relationship between LVH detected by ECG and the presence of proteinuria among such subjects.

本文言語English
ページ(範囲)249-255
ページ数7
ジャーナルNagoya journal of medical science
80
2
DOI
出版ステータスPublished - 01-05-2018
外部発表はい

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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