Light and electron microscopic observation of intracytoplasmic inclusion bodies in the locus coeruleus of the hamster

Yoshimitsu Y. Katoh, Eriko Yamazaki, Kanako Taniguti, Keiki Yamada, Genzoh Isomura

研究成果: Article査読

1 被引用数 (Scopus)

抄録

The authors previously demonstrated that intracytoplasmic inclusion bodies (1-3 μm) in the mouse locus coeruleus under light and electron microscopy are characteristically stained using the Holmes modified method. We reported that one inclusion body existed in almost all neurons of the locus coeruleus. The present study examined whether similar inclusion bodies are present in the Syrian hamster (weight, about 60 g). Paraffin sections stained with the modified Holmes' method displayed numerous small inclusion bodies in the cytoplasm of cells in the locus coeruleus. Epon sections (1 μm thick) stained using toluidine blue were observed under light microscopy, and numerous small inclusion bodies were again observed. Under electron microscopy observation, inclusion bodies (<1 μm in diameter) predominantly comprised small granular materials, similar to those described by previous investigators. Although inclusion bodies were devoid of a limiting membrane, the relationship to cytoplasmic organelles was unclear. However, free and polyribosomes were occasionally noted in close proximity to inclusion bodies. Inclusion bodies may thus be formed from ribosomes. Intracytoplasmic inclusion bodies in the hamster locus coeruleus differed in appearance compared with inclusion bodies in the mouse locus coeruleus.

本文言語English
ページ(範囲)129-134
ページ数6
ジャーナルArchives of Histology and Cytology
69
2
DOI
出版ステータスPublished - 2006

All Science Journal Classification (ASJC) codes

  • 組織学

フィンガープリント

「Light and electron microscopic observation of intracytoplasmic inclusion bodies in the locus coeruleus of the hamster」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル