Long-term clinical outcomes after self-expandable bare nitinol stent implantation for femoropopliteal occlusive disease in hemodialysis patients

Ryuta Ito, Hideki Ishii, Satoru Oshima, Takuya Nakayama, Hiroshi Takahashi, Takashi Sakakibara, Motohiko Kakuno, Toyoaki Murohara

研究成果: Article査読

抄録

Objectives: To compare the long-term clinical outcomes after self-expandable bare nitinol stent (BNS) implantation between hemodialysis (HD) and non-HD patients with femoropopliteal (FP) disease. Background: Although a BNS has been commonly used in patients with FP disease, the long-term efficacy of BNSs in HD patients remains unknown. Methods: In total, 427 HD patients treated with a BNS for FP disease were enrolled, along with 157 non-HD patients as a control group. Over the following 5 years, the incidence of target lesion revascularization (TLR), major amputation and mortality was investigated. We also performed propensity-score matching analysis. Results: The 5-year TLR rate (45.2 vs. 32.5%, p =.013) and mortality rate (39.3 vs. 14.0%, p =.0002) were significantly higher in the HD group than in the non-HD group. The major amputation rate was comparable between the groups (7.2% in the HD group vs. 2.8% in the non-HD group, p =.16). In the propensity-score-matched cohort, the TLR rate, and mortality rate were remained higher in the HD group than in the non-HD group (48.9 vs. 34.1%, hazard ratio [HR] 2.11, 95% confidence interval [CI] 1.30–3.49, p =.0024, and 47.9 vs. 12.0%, HR 3.38, 95% CI 1.86–6.56, p <.0001, respectively). The adjusted amputation rate was consistently similar between the groups (1.7% in the HD group vs. 2.7% in the non-HD group, HR 0.90, 95% CI 0.26–2.99, p =.86). Conclusions: The TLR rate and mortality at 5 years post BNS implantation for FP disease were significantly higher in HD patients than in non-HD patients, though the limb salvage rate was similar.

本文言語English
ページ(範囲)318-324
ページ数7
ジャーナルCatheterization and Cardiovascular Interventions
97
2
DOI
出版ステータスPublished - 01-02-2021

All Science Journal Classification (ASJC) codes

  • 放射線学、核医学およびイメージング
  • 循環器および心血管医学

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