Long-term outcome of trabeculectomy with adjunct mitomycin-C for neovascular glaucoma

Purpose: To evaluate the long-term outcome of trabeculectomy for neovascular glaucoma with adjunct use of mitomycin C. Objects and Method: This retrospective study was made on 50 eyes of neovascular glaucoma that received mitomycin C-assisted trabeculectomy. Vitrectomy had been performed on 38 eyes. Another series of similarly treated 37 eyes of primary open-angle glaucoma (POAG) served as control. Outcome after surgery was evaluated by survical curve analysis of Kaplan-Meier setting 20 mmHg of intraocular pressure as criterium without topical medication. Results: The 3-year survival rate without medication was 51.3% in POAG and 32.3% in neovascular glaucoma. The difference was not significant. Survival rate with topical medication was 59.7% and 77.7% respectively. The difference was significant. There was no difference in 3-year survival rate between eyes with or without prior vitrectomy. Conclusion: Mitomycin C-assisted trabeculectomy was useful in neovascular glaucoma but was less effective than in POAG.