Long-term survival of young women receiving fertility-sparing surgery for ovarian cancer in comparison with those undergoing radical surgery

H. Kajiyama, K. Shibata, M. Mizuno, T. Umezu, S. Suzuki, A. Nawa, M. Kawai, T. Nagasaka, F. Kikkawa

研究成果: Article

41 被引用数 (Scopus)

抄録

Objectives:To compare the clinical outcome of patients with stage I epithelial ovarian cancer (EOC) who received with fertility-sparing surgery (FSS) with those who underwent radical surgery (RS). Methods: After a central pathological review and search of the medical records from multiple institutions, a total of 572 patients were retrospectively evaluated. All patients were divided into three groups: group A FSS (n=74); age, ≤40; groups B and C RS; age, 40>(B), n=52; 40<(C), n=446. Results: Five-year overall survival (OS) and disease-free survival (DFS) rates of patients in the groups were as follows: group A, 90.8% (OS)/87.9% (DFS); group B, 88.3% (OS)/84.4% (DFS); group C, 90.6% (OS)/85.3% (DFS), respectively (OS, P=0.802; DFS, P=0.765). Additionally, there was no significant difference in OS and DFS among the three groups stratified to stage IA or IC (OS (IA), P=0.387; DFS (IA), P=0.314; OS (IC), P=0.993; DFS (IC), P=0.990, respectively). Furthermore, patients with a grade 1-2 or 3 tumours in the FSS group did not have a poorer prognosis than those in the RS group.Conclusions:Stage I EOC patients treated with FSS showed an acceptable prognosis compared with those who underwent RS.

本文言語English
ページ(範囲)1288-1294
ページ数7
ジャーナルBritish Journal of Cancer
105
9
DOI
出版ステータスPublished - 25-10-2011

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

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