TY - JOUR
T1 - Low-level release of Shiga-like toxin (Verocytotoxin) and endotoxin from enterohemorrhagic Escherichia coli treated with imipenem
AU - Takahashi, Kazuko
AU - Narita, Kayou
AU - Kato, Yutaka
AU - Sugiyama, Tsuyoshi
AU - Koide, Naoki
AU - Yoshida, Tomoaki
AU - Yokochi, Takashi
PY - 1997/10
Y1 - 1997/10
N2 - Shiga-like toxin (SLT) and endotoxin may participate in the pathogenesis of enterohemorrhagic Escherichia coli (EHEC) infection. Levels of release of SLT and endotoxin from EHEC treated in vitro with antibiotics were estimated. There were differential levels of release of SLT and endotoxin from EHEC treated with different antibiotics. Treatment of EHEC strains, namely, E. coli O157, O111, and O26, with imipenem induced much lower levels of release of SLT and endotoxin than treatment with ceftazidime.
AB - Shiga-like toxin (SLT) and endotoxin may participate in the pathogenesis of enterohemorrhagic Escherichia coli (EHEC) infection. Levels of release of SLT and endotoxin from EHEC treated in vitro with antibiotics were estimated. There were differential levels of release of SLT and endotoxin from EHEC treated with different antibiotics. Treatment of EHEC strains, namely, E. coli O157, O111, and O26, with imipenem induced much lower levels of release of SLT and endotoxin than treatment with ceftazidime.
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U2 - 10.1128/aac.41.10.2295
DO - 10.1128/aac.41.10.2295
M3 - Article
C2 - 9333067
AN - SCOPUS:0030764822
SN - 0066-4804
VL - 41
SP - 2295
EP - 2296
JO - Antimicrobial agents and chemotherapy
JF - Antimicrobial agents and chemotherapy
IS - 10
ER -
