Machine learning for lung CT texture analysis: Improvement of inter-observer agreement for radiological finding classification in patients with pulmonary diseases

Yoshiharu Ohno, Kota Aoyagi, Daisuke Takenaka, Takeshi Yoshikawa, Aina Ikezaki, Yasuko Fujisawa, Kazuhiro Murayama, Hidekazu Hattori, Hiroshi Toyama

研究成果: Article査読

抄録

Purpose: To evaluate the capability ML-based CT texture analysis for improving interobserver agreement and accuracy of radiological finding assessment in patients with COPD, interstitial lung diseases or infectious diseases. Materials and methods: Training cases (n = 28), validation cases (n = 17) and test cases (n = 89) who underwent thin-section CT at a 320-detector row CT with wide volume scan and two 64-detector row CTs with helical scan were enrolled in this study. From 89 CT data, a total of 350 computationally selected ROI including normal lung, emphysema, nodular lesion, ground-glass opacity, reticulation and honeycomb were evaluated by three radiologists as well as by the software. Inter-observer agreements between consensus reading with and without using the software or software alone and standard references determined by consensus of pulmonologists and chest radiologists were determined using κ statistics. Overall distinguishing accuracies were compared among all methods by McNemar's test. Results: Agreements for consensus readings obtained with and without the software or the software alone with standard references were determined as significant and substantial or excellent (with the software: κ = 0.91, p < 0.0001; without the software: κ = 0.81, p < 0.0001; the software alone: κ = 0.79, p < 0.0001). Overall differentiation accuracy of consensus reading using the software (94.9 [332/350] %) was significantly higher than that of consensus reading without using the software (84.3 [295/350] %, p < 0.0001) and the software alone (82.3 [288/350] %, p < 0.0001). Conclusion: ML-based CT texture analysis software has potential for improving interobserver agreement and accuracy for radiological finding assessments in patients with COPD, interstitial lung diseases or infectious diseases.

本文言語English
論文番号109410
ジャーナルEuropean journal of radiology
134
DOI
出版ステータスPublished - 01-2021

All Science Journal Classification (ASJC) codes

  • 放射線学、核医学およびイメージング

フィンガープリント

「Machine learning for lung CT texture analysis: Improvement of inter-observer agreement for radiological finding classification in patients with pulmonary diseases」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル