Metastasis of uterine leiomyosarcoma to the pancreas - Usefulness and limitations of EUS-FNA

Takeshi Ogura, Kenji Yamao, Susumu Hijioka, Kazuo Hara, Akira Sawaki, Nobumasa Mizuno, Yasumasa Niwa, Masahiro Tajika, Hiroki Kawai, Shinya Kondo, Akira Saeki, Asana Akabane, Shin Haba, Teruko Tomono, Satoshi Shimizu, Yasuhiro Shimizu, Kazuki Hosoda, Yasushi Yatabe

研究成果: Article査読

3 被引用数 (Scopus)

抄録

A woman in her 60's presented with a tumor of the pancreatic body. Pan-hysterectomy had been performed under a diagnosis of uterine leiomyoma 11 years previously. A sample obtained by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) revealed the histopathological proliferation of spindle-shaped bundles of atypical cells, and immunohistochemical staining demonstrated that these cells were positive for KIT. Therefore, distal pancreatectomy was performed under a diagnosis of pancreatic gastrointestinal stromal tumor (GIST). Immunohistochemical staining of surgical specimens demonstrated that the tumor cells were positive for desmin and negative for KIT and CD34. The low-grade leiomyosarcoma in pathological specimens of the uterine myoma obtained 11 years previously histologically resembled the pathological findings of the pancreatic specimens except for atypical nuclei and mitotic cells. Therefore, the final diagnosis was extremely rare metastatic leiomyosarcoma of the pancreas. Herein, we report metastasis of uterine leiomyosarcoma to the pancreas and discuss the usefulness and limitations of EUS-FNA.

本文言語English
ページ(範囲)987-996
ページ数10
ジャーナルJournal of Japanese Society of Gastroenterology
108
6
出版ステータスPublished - 06-2011

All Science Journal Classification (ASJC) codes

  • 消化器病学

フィンガープリント

「Metastasis of uterine leiomyosarcoma to the pancreas - Usefulness and limitations of EUS-FNA」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル