Migration activity of microglia and macrophages into rat brain

F. Imai, M. Sawada, H. Suzuki, N. Kiya, M. Hayakawa, T. Nagatsu, T. Marunouchi, T. Kanno

研究成果: Article査読

32 被引用数 (Scopus)

抄録

We examined the entry of intra-arterially injected microglia and macrophages into the brain using a rat muscle graft model to compare their respective abilities to invade the brain parenchyma. Isolated microglia without any activation treatment entered into the brain with or without the muscle graft, while macrophages activated by phorbol 12-myristate-13-acetate (PMA) entered the brain only in the presence of the muscle graft. These results suggest that microglia have a higher affinity for the brain than macrophages.

本文言語English
ページ(範囲)49-52
ページ数4
ジャーナルNeuroscience Letters
237
1
DOI
出版ステータスPublished - 14-11-1997

All Science Journal Classification (ASJC) codes

  • 神経科学(全般)

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