Modeling the Positive Symptoms of Schizophrenia

Tursun Alkam, Toshitaka Nabeshima

研究成果: Chapter

1 被引用数 (Scopus)

抄録

The positive symptoms of schizophrenia such as disorganized speech, delusions, and hallucinations seem to unique to humans. Current research on schizophrenia in general has remained very challenging, thanks to growing numbers in theories about the cause and progression of the disease. A lack of behavioral methods to selectively study positive symptom-like behaviors or alternative behaviors has made it even more challenging to develop animal models with rational pathology of schizophrenia. However, emerging neuroimaging findings and rich information obtained from several decades of hallucinogen studies are encouraging to establish animal models to explore various causative theories for positive symptoms in schizophrenia. In this chapter, we review neuroimaging and pharmacological findings related to delusions and hallucinations and briefly introduce behavioral methods to investigate positive symptom-related behaviors in animal models of schizophrenia.

本文言語English
ホスト出版物のタイトルHandbook of Behavioral Neuroscience
出版社Elsevier B.V.
ページ39-54
ページ数16
DOI
出版ステータスPublished - 01-01-2016
外部発表はい

出版物シリーズ

名前Handbook of Behavioral Neuroscience
23
ISSN(印刷版)1569-7339

All Science Journal Classification (ASJC) codes

  • 認知神経科学
  • 行動神経科学

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