Molecular and immunohistochemical detection of rotavirus in urinary sediment cells of children with rotavirus gastroenteritis

T. Yokoyama, N. Sugimoto, K. Taniguchi, S. Komoto, T. Yuno, K. Ohta, H. Hashimoto, A. Seno, A. Ashida, M. Fujieda, S. Nishio, K. Ueno, M. Shimizu, A. Yachie

研究成果: Article

3 引用 (Scopus)

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This is the first report showing that rotavirus infects the urinary sediment cells in immunocompetent children with rotavirus gastroenteritis. We found that inclusion-bearing cells were frequently detected in the urine samples of patients with rotavirus gastroenteritis. These cells were positive for cytokeratin, which was sometimes coexpressed with rotavirus antigen, in our immunohistochemical analysis. Moreover, in nested RT-PCR experiments, we detected rotavirus double-stranded RNA in some urine samples of patients with rotavirus gastroenteritis. We concluded that rotavirus could lead to infection of the urinary sediment cells concomitantly with rotavirus gastroenteritis.

元の言語English
ページ(範囲)1190-1193
ページ数4
ジャーナルClinical Microbiology and Infection
17
発行部数8
DOI
出版物ステータスPublished - 08-2011

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All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

これを引用

Yokoyama, T., Sugimoto, N., Taniguchi, K., Komoto, S., Yuno, T., Ohta, K., Hashimoto, H., Seno, A., Ashida, A., Fujieda, M., Nishio, S., Ueno, K., Shimizu, M., & Yachie, A. (2011). Molecular and immunohistochemical detection of rotavirus in urinary sediment cells of children with rotavirus gastroenteritis. Clinical Microbiology and Infection, 17(8), 1190-1193. https://doi.org/10.1111/j.1469-0691.2011.03522.x