Molecular and virological evidence of viral activation from chromosomally integrated human herpesvirus 6A in a patient with X-linked severe combined immunodeficiency

Akifumi Endo; Ken Watanabe; Tamae Ohye; Kyoko Suzuki; Tomoyo Matsubara; Norio Shimizu; Hiroki Kurahashi; Tetsushi Yoshikawa; Harutaka Katano; Naoki Inoue; Kohsuke Imai; Masatoshi Takagi; Tomohiro Morio; Shuki Mizutani

doi:10.1093/cid/ciu323

Molecular and virological evidence of viral activation from chromosomally integrated human herpesvirus 6A in a patient with X-linked severe combined immunodeficiency

Akifumi Endo
, Ken Watanabe
, Tamae Ohye
, Kyoko Suzuki
, Tomoyo Matsubara
, Norio Shimizu
, Hiroki Kurahashi
, Tetsushi Yoshikawa
, Harutaka Katano
, Naoki Inoue
, Kohsuke Imai
, Masatoshi Takagi
, Tomohiro Morio
, Shuki Mizutani

研究成果: ジャーナルへの寄稿 › 学術論文 › 査読

128 被引用数 (Scopus)

抄録

It has been unclear whether chromosomally integrated human herpesvirus 6 (ciHHV-6) can be activated with pathogenic effects on the human body. We present molecular and virological evidence of ciHHV-6A activation in a patient with X-linked severe combined immunodeficiency. These findings have significant implications for the management of patients with ciHHV-6.

本文言語	英語
ページ（範囲）	545-548
ページ数	4
ジャーナル	Clinical Infectious Diseases
巻	59
号	4
DOI	https://doi.org/10.1093/cid/ciu323
出版ステータス	出版済み - 15-08-2014
外部発表	はい

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All Science Journal Classification (ASJC) codes

微生物学（医療）
感染症

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10.1093/cid/ciu323

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引用スタイル

Endo, A., Watanabe, K., Ohye, T., Suzuki, K., Matsubara, T., Shimizu, N., Kurahashi, H., Yoshikawa, T., Katano, H., Inoue, N., Imai, K., Takagi, M., Morio, T., & Mizutani, S. (2014). Molecular and virological evidence of viral activation from chromosomally integrated human herpesvirus 6A in a patient with X-linked severe combined immunodeficiency. Clinical Infectious Diseases, 59(4), 545-548. https://doi.org/10.1093/cid/ciu323

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abstract = "It has been unclear whether chromosomally integrated human herpesvirus 6 (ciHHV-6) can be activated with pathogenic effects on the human body. We present molecular and virological evidence of ciHHV-6A activation in a patient with X-linked severe combined immunodeficiency. These findings have significant implications for the management of patients with ciHHV-6.",

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author = "Akifumi Endo and Ken Watanabe and Tamae Ohye and Kyoko Suzuki and Tomoyo Matsubara and Norio Shimizu and Hiroki Kurahashi and Tetsushi Yoshikawa and Harutaka Katano and Naoki Inoue and Kohsuke Imai and Masatoshi Takagi and Tomohiro Morio and Shuki Mizutani",

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Endo, A, Watanabe, K, Ohye, T, Suzuki, K, Matsubara, T, Shimizu, N, Kurahashi, H , Yoshikawa, T, Katano, H, Inoue, N, Imai, K, Takagi, M, Morio, T & Mizutani, S 2014, 'Molecular and virological evidence of viral activation from chromosomally integrated human herpesvirus 6A in a patient with X-linked severe combined immunodeficiency', Clinical Infectious Diseases, vol. 59, no. 4, pp. 545-548. https://doi.org/10.1093/cid/ciu323

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T1 - Molecular and virological evidence of viral activation from chromosomally integrated human herpesvirus 6A in a patient with X-linked severe combined immunodeficiency

AU - Endo, Akifumi

AU - Watanabe, Ken

AU - Ohye, Tamae

AU - Suzuki, Kyoko

AU - Matsubara, Tomoyo

AU - Shimizu, Norio

AU - Kurahashi, Hiroki

AU - Yoshikawa, Tetsushi

AU - Katano, Harutaka

AU - Inoue, Naoki

AU - Imai, Kohsuke

AU - Takagi, Masatoshi

AU - Morio, Tomohiro

AU - Mizutani, Shuki

PY - 2014/8/15

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KW - CiHHV-6

KW - HHV-6

KW - Hemophagocytic Syndrome

KW - Thrombotic microangiopathy

KW - X-SCID

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