Molecular biology of glioma

Tomotoshi Marumoto, Hideyuki Saya

研究成果: Chapter

53 被引用数 (Scopus)

抄録

Glioblastoma (GBM) is the most aggressive form of glioma. Despite ceaseless efforts by researchers and physicians to find new therapeutic strategies, there have been no significant advances in the treatment of GBMs for several decades and most patients with GBM die within one and half years of diagnosis. Undoubtedly, one reason for this is the insufficient understanding of the initiation and progression of GBMs at the molecular level. However, recent information regarding the genetic and epigenetic alterations and the microRNAs that are aberrantly activated or inactivated in GBMs has helped elucidate the formation of GBM in more detail. Here, we describe recent advances in the understanding of the biology of GBMs.

本文言語English
ホスト出版物のタイトルGlioma
ホスト出版物のサブタイトルImmunotherapeutic Approaches
編集者Ryuya Yamanaka
ページ2-11
ページ数10
DOI
出版ステータスPublished - 2012
外部発表はい

出版物シリーズ

名前Advances in Experimental Medicine and Biology
746
ISSN(印刷版)0065-2598

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

フィンガープリント 「Molecular biology of glioma」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル