Molecular epidemiology of KPC-producing Escherichia coli: Occurrence of ST131-fimH30 subclone harboring pKpQIL-like IncFIIk plasmid

Jessica A. O'Hara, Fupin Hu, Chulsoo Ahn, Jeremy Nelson, Jesabel I. Rivera, Anthony W. Pasculle, Yohei Doi

研究成果: Article

30 引用 (Scopus)

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Of 20 Klebsiella pneumoniae carbapenemase (KPC)-producing Escherichia coli isolates identified at hospitals in western Pennsylvania, 60% belonged to the epidemic ST131-fimH30 subclone. IncFIIk was the most common replicon type for the blaKPC-carrying plasmids (n = 8). All IncFIIk plasmids possessed a scaffold similar to that of pKpQIL, and seven of them were borne by ST131-fimH30 isolates. IncN plasmids conferred resistance to trimethoprim-sulfamethoxazole, and IncA/C plasmids conferred resistance to gentamicin. Three blaKPC-carrying plasmids (IncA/C and IncN) possessed blaSHV-7/12 and qnrA1 or qnrS1.

元の言語English
ページ(範囲)4234-4237
ページ数4
ジャーナルAntimicrobial agents and chemotherapy
58
発行部数7
DOI
出版物ステータスPublished - 07-2014
外部発表Yes

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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