Movement of mitral fibrous components in an isolated porcine working heart model

Akinori Tamenishi, Yoshimori Araki, Shunei Saito, Hideki Oshima, Yuichi Ueda, Akihiko Usui

研究成果: ジャーナルへの寄稿学術論文査読

1 被引用数 (Scopus)

抄録

Background There is little research regarding the movement of mitral fibrous components. We analyzed changes in mitral fibrous components in normal and deteriorated isolated working swine hearts. Methods In 5 swine hearts, 6 sonomicrometry transducers were placed around the mitral annulus and 2 in the papillary muscle tip. During the working cycle, we evaluated the annular dimension and calculated the contraction range and contraction ratio during the cardiac cycle in normal and deteriorated modes. Results The transverse (24.5"‰±"‰2.3 vs. 27.4"‰±"‰2.4"‰mm) and posterior longitudinal diameter (18.3"‰±"‰7.0 vs. 22.5"‰±"‰5.5"‰mm) increased significantly in deteriorated mode. The contraction range in transverse (1.8"‰±"‰0.6 vs. 0.8"‰±"‰0.7"‰mm) and posterior longitudinal (1.6"‰±"‰0.6 vs. 0.8"‰±"‰0.3"‰mm) diameters decreased significantly in deteriorated mode. The contraction range of the strut chordae was less than 1.0"‰mm in both modes, with no significant differences. The contraction ratio of the anterior strut chordae was significantly reduced in deteriorated mode (3.2"‰±"‰1.1% vs. 2.2"‰±"‰1.1%). The contraction ratio of the annulus was significantly lower in deteriorated mode with respect to transverse (6.9"‰±"‰2.1% vs. 2.9"‰±"‰2.9%) and longitudinal (13.3"‰±"‰4.5% vs. 8.6"‰±"‰5.1%) diameters. Conclusions In the deteriorated hearts, the mitral annulus was dilated and contractility decreased. The length of the strut chordae differed 1"‰mm between the deteriorated and normal modes; however, the contraction ratio of the anterior chordae during the cardiac cycle was reduced, indicating increased stretching.

本文言語英語
ページ(範囲)917-922
ページ数6
ジャーナルAsian Cardiovascular and Thoracic Annals
23
8
DOI
出版ステータス出版済み - 23-10-2015
外部発表はい

All Science Journal Classification (ASJC) codes

  • 外科
  • 呼吸器内科
  • 循環器および心血管医学

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