Myelodysplastic syndrome evolving into a myeloproliferative disorder: One disease or two?

Kazuma Ohyashiki, Kenji Yokoyama, Yukihiko Kimura, Junko H. Ohyashiki, Toshikazu Ito, Tadatoshi Kuratsuji, Satoru Komatsumoto, Masaharu Nara, Keisuke Toyama

研究成果: Review article査読

17 被引用数 (Scopus)

抄録

We report two patients who had been initially diagnosed as having a myelodysplastic syndrome but subsequently progressed into a leukothrombocytosis state which mimicked a chronic myeloproliferative disorder. Both patients had anemia and mild neutropenia without thrombocytopenia at the time of their diagnosis of myelodysplastic syndrome, and dyshematopoietic features were present in the bone marrow. After treatment with vitamin D3 for 7 and 18 months, respectively, they developed leukothrombocytosis which responded to hydroxyurea. We speculate that these and other similar patients with this unusual course might constitute an entity distinct from the typical myelodysplastic syndromes or chronic myeloproliferative disorders.

本文言語English
ページ(範囲)338-340
ページ数3
ジャーナルLeukemia
7
2
出版ステータスPublished - 02-1993
外部発表はい

All Science Journal Classification (ASJC) codes

  • 血液学
  • 腫瘍学
  • 癌研究

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