Neuronal intranuclear inclusion disease presenting with dysphagia: a report of three cases

Yoichiro Aoyagi, Michiko Taya, Miho Ohashi, Eiichi Saitoh

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Neuronal intranuclear inclusion disease (NIID) is a rare neurodegenerative disease that is pathologically characterized by the presence of eosinophilic hyaline intranuclear inclusions in neurons, astrocytes, and specific somatic cells. Previously reported cases of NIID displayed various neurological symptoms, including dementia, muscle weakness, ataxia, etc. However, dysphagia associated with NIID have rarely been reported. Here, we report on three cases of NIID with dysphagia. Bolus mastication and transport were impaired in all three cases. Delay of the initiation of pharyngeal swallowing and silent aspiration was observed in two cases. Combined with the brain magnetic resonance imaging (MRI) findings, oropharyngeal dysphagia associated with NIID was suggested to be attributed to diffuse subcortical lesions.

本文言語English
ページ(範囲)252-257
ページ数6
ジャーナルNeurocase
DOI
出版ステータスPublished - 2020

All Science Journal Classification (ASJC) codes

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

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